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QuickView for SRP;jsessionid=B6E009A4270086ECEDCEB12C1C9C17B5;jsessionid=1D817BD1162CFCF2C690B8AF7AF87E14 (gene)


Gene Symbol:
Gata4 Mus musculus Mus musculus
Full name:
GATA binding protein 4
Synonyms:
Gata-4, transcription factor GATA-4, GATA-binding factor 4
Genomic Location:
Chr 14: 63817752-63864097
Orthologs:
Homo sapiens Rattus norvegicus D. melanogaster Saccharomyces cerevisiae Macaca mulatta Danio rerio Bos taurus Gallus gallus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):





GO Molecular Function

sequence-specific DNA binding | transcription factor activity, transcription factor binding | kinase binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | enhancer binding | cation binding | protein kinase binding | transcription factor activity, RNA polymerase II transcription factor binding | proximal promoter sequence-specific DNA binding | enzyme binding | nucleic acid binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | chromatin binding | co-SMAD binding | NFAT protein binding | enhancer sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | ion binding | organic cyclic compound binding | transcription coactivator activity | transcription regulatory region sequence-specific DNA binding | protein binding | zinc ion binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor binding | RNA polymerase II transcription factor binding | activating transcription factor binding | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | transition metal ion binding | transcription coregulator activity | SMAD binding | metal ion binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | signal transduction involved in regulation of gene expression | regulation of ERK1 and ERK2 cascade | SMAD protein signal transduction | regulation of muscle system process | transcription factor activity, transcription factor binding | positive regulation of macromolecule biosynthetic process | regulation of cellular response to oxidative stress | regulation of response to oxidative stress | developmental process involved in reproduction | muscle tissue development | atrioventricular valve formation | regulation of localization | morphogenesis of an epithelium | positive regulation of striated muscle tissue development | gonad development | regulation of programmed cell death | negative regulation of cellular response to oxidative stress | foregut morphogenesis | regulation of autophagy | response to hormone | cell growth involved in cardiac muscle cell development | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of developmental process | regulation of heart growth | regulation of cardiac muscle cell apoptotic process | cell differentiation | negative regulation of tissue remodeling | respiratory tube development | male gamete generation | striated muscle cell development | response to drug | organ growth | positive regulation of phosphate metabolic process | cardiac cell development | mesenchyme development | cardiac atrium morphogenesis | blood vessel morphogenesis | regulation of cardiac muscle cell proliferation | pattern specification process | positive regulation of cellular biosynthetic process | cellular process | diaphragm development | epithelial tube morphogenesis | heart morphogenesis | negative regulation of signaling | developmental growth | determination of left/right symmetry | reproductive system development | canonical Wnt signaling pathway | multicellular organismal reproductive process | regulation of striated muscle tissue development | negative regulation of apoptotic process | digestive tract morphogenesis | Sertoli cell differentiation | regulation of cell cycle | response to growth factor | positive regulation of nitrogen compound metabolic process | transcription factor activity, RNA polymerase II transcription factor binding | negative regulation of cellular metabolic process | tissue development | regulation of cell differentiation | gamete generation | muscle structure development | muscle cell differentiation | skeletal muscle organ development | negative regulation of apoptotic signaling pathway | regeneration | regulation of angiogenesis | regulation of protein kinase B signaling | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | transdifferentiation | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | negative regulation of oxidative stress-induced cell death | epithelium development | cellular aromatic compound metabolic process | coronary vasculature morphogenesis | diaphragm morphogenesis | development of primary sexual characteristics | muscle organ morphogenesis | regulation of vasculature development | response to stimulus | cardiac right ventricle morphogenesis | vasculature development | muscle cell development | lung lobe morphogenesis | respiratory system development | positive regulation of cardioblast differentiation | positive regulation of protein metabolic process | determination of heart left/right asymmetry | response to stress | skeletal muscle tissue development | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | tube morphogenesis | regulation of blood circulation | regulation of cardiac muscle cell contraction | cardiac muscle tissue development | vasculogenesis involved in coronary vascular morphogenesis | physiological cardiac muscle hypertrophy | reproduction | atrioventricular valve morphogenesis | positive regulation of vascular endothelial growth factor production | cardiovascular system development | embryonic digestive tract morphogenesis | cardiac ventricle morphogenesis | cellular nitrogen compound metabolic process | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | positive regulation of BMP signaling pathway | positive regulation of RNA biosynthetic process | cellular biosynthetic process | septum secundum development | embryo development | heart growth | cell-cell signaling | cell surface receptor signaling pathway involved in cell-cell signaling | blood vessel development | anterior/posterior pattern specification | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | response to BMP | cellular response to hormone stimulus | endocardial cushion development | epithelial cell fate commitment | system development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | Wnt signaling pathway | heart valve formation | multicellular organism development | regulation of MAPK cascade | regulation of BMP signaling pathway | negative regulation of striated muscle cell apoptotic process | response to follicle-stimulating hormone | positive regulation of muscle organ development | regulation of muscle contraction | regulation of phosphorylation | embryonic digestive tract development | wound healing | atrial septum secundum morphogenesis | seminiferous tubule development | positive regulation of cell cycle | determination of bilateral symmetry | regulation of gene expression | outflow tract morphogenesis | response to lipid | cellular response to gonadotropin stimulus | embryonic heart tube morphogenesis | coronary vasculature development | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | animal organ morphogenesis | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | cardiac atrium development | positive regulation of intracellular signal transduction | cardiocyte differentiation | regulation of cellular component movement | regulation of transcription by RNA polymerase II | endoderm formation | positive regulation of cell differentiation | negative regulation of cardiac muscle cell apoptotic process | cardiac muscle hypertrophy | biosynthetic process | positive regulation of cardiac muscle cell proliferation | mitral valve development | aortic valve morphogenesis | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | cardiac muscle cell development | negative regulation of connective tissue replacement | cardiac septum morphogenesis | digestive tract development | heart looping | septum primum development | regulation of apoptotic signaling pathway | regulation of heart contraction | negative regulation of autophagy | gastrulation with mouth forming second | regulation of striated muscle contraction | response to estrogen | regulation of muscle cell apoptotic process | chordate embryonic development | striated muscle tissue development | mitral valve formation | cell communication | regulation of cellular metabolic process | transmembrane receptor protein serine/threonine kinase signaling pathway | semi-lunar valve development | regulation of cardiac muscle contraction | regulation of protein metabolic process | positive regulation of signal transduction | lung lobe formation | vasculogenesis | heart development | positive regulation of cell proliferation | regulation of protein phosphorylation | embryo development ending in birth or egg hatching | transcription coactivator activity | regulation of RNA metabolic process | regulation of stem cell differentiation | response to retinoic acid | striated muscle cell differentiation | intestinal epithelial cell differentiation | regulation of cellular response to growth factor stimulus | embryonic morphogenesis | mitral valve morphogenesis | cardiac muscle tissue growth | multicellular organism reproduction | embryonic organ morphogenesis | development of primary male sexual characteristics | tricuspid valve development | positive regulation of organ growth | heart valve development | ventricular septum development | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | regionalization | cardiac ventricle development | positive regulation of protein modification process | regulation of growth | response to organic substance | regulation of cardiac muscle tissue development | tissue morphogenesis | digestive system development | male sex differentiation | response to wounding | response to mechanical stimulus | regulation of intracellular signal transduction | ventricular cardiac muscle tissue development | embryonic heart tube development | anatomical structure development | cell surface receptor signaling pathway | metabolic process | negative regulation of response to oxidative stress | cell fate commitment | regulation of RNA biosynthetic process | negative regulation of programmed cell death | embryonic organ development | male gonad development | atrial septum primum morphogenesis | regulation of tissue remodeling | negative regulation of muscle cell apoptotic process | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | atrioventricular canal development | heart valve morphogenesis | organic substance metabolic process | negative regulation of gene expression | animal organ development | gene expression | cardiac muscle tissue regeneration | positive regulation of ERK1 and ERK2 cascade | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | regulation of phosphate metabolic process | positive regulation of muscle tissue development | atrioventricular valve development | transcription, DNA-templated | positive regulation of cytokine production | response to gonadotropin | positive regulation of stem cell differentiation | positive regulation of MAPK cascade | cellular response to follicle-stimulating hormone stimulus | lung development | atrial septum development | anatomical structure formation involved in morphogenesis | cardiac muscle cell differentiation | BMP signaling pathway | regulation of cell communication | negative regulation of signal transduction | positive regulation of developmental growth | signaling | positive regulation of growth | regulation of transcription, DNA-templated | cell development | regulation of developmental growth | positive regulation of phosphorylation | regulation of cytokine production | endoderm development | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | regulation of organ growth | reproductive structure development | regulation of developmental process | developmental process | spermatogenesis | cardiac septum development | embryonic heart tube anterior/posterior pattern specification | tube development | positive regulation of transcription, DNA-templated | aortic valve development | atrial septum morphogenesis | developmental cell growth | positive regulation of nucleic acid-templated transcription | positive regulation of heart growth | transcription coregulator activity | lung morphogenesis | epithelial cell differentiation | tricuspid valve formation | formation of primary germ layer | positive regulation of transcription by RNA polymerase II | cardiac chamber development | heterocycle metabolic process | regulation of vascular endothelial growth factor production | in utero embryonic development | positive regulation of metabolic process | regulation of actin filament-based process | cellular response to BMP stimulus | tricuspid valve morphogenesis | gastrulation | regulation of cardioblast differentiation | lung lobe development | embryonic foregut morphogenesis | cellular metabolic process | cellular response to organic substance | regulation of cell death | sex differentiation | positive regulation of cardiac muscle tissue development | negative regulation of cell death | circulatory system development | muscle hypertrophy | tissue regeneration | sexual reproduction | positive regulation of angiogenesis | skeletal muscle cell differentiation | muscle organ development | muscle system process | cardiac muscle hypertrophy in response to stress | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | cellular response to growth factor stimulus | regulation of muscle organ development | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

nuclear transcription factor complex | chromosome | intracellular membrane-bounded organelle | RNA polymerase II transcription factor complex | cell | nuclear lumen | transcription factor complex | intracellular organelle | nuclear body | protein-containing complex | nucleoplasm | chromatin | nuclear chromosome | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear chromatin | intracellular