QuickView for SUFU;jsessionid=CB0B649FC3076049C141AB19D14CB00B;jsessionid=F8A3AC9261A5B5CE491ED6001474BE79 (gene)
- Gene Symbol:
- Sufu
Mus musculus - Full name:
- SUFU negative regulator of hedgehog signaling
- Synonyms:
- Su(fu), suppressor of fused homolog
- Genomic Location:
- Chr 19: 46471408-46561150
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Bos taurus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
AACTTT_UNKNOWN , GATA1_01 , EVI1_05 , ACTAYRNNNCCCR_UNKNOWN , GATA1_02 , ARGGGTTAA_UNKNOWN , AP1_Q2 , AP2_Q6 , NFKB_Q6 , NRF1_Q6
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
beta-catenin binding | kinase binding | protein kinase binding | enzyme binding | protein binding | transcription factor binding
GO Biological Process
negative regulation of embryonic development | morphogenesis of an epithelium | spinal cord motor neuron differentiation | negative regulation of cellular process | negative regulation of RNA biosynthetic process | cell differentiation | ventral spinal cord interneuron fate commitment | nervous system development | neurogenesis | generation of neurons | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning | negative regulation of proteolysis | pattern specification process | cellular process | cell fate specification | localization | epithelial tube morphogenesis | negative regulation of ubiquitin-dependent protein catabolic process | heart morphogenesis | negative regulation of signaling | central nervous system neuron differentiation | determination of left/right symmetry | regulation of embryonic development | negative regulation of nucleic acid-templated transcription | macromolecule localization | regulation of proteolysis | regulation of smoothened signaling pathway | negative regulation of cellular metabolic process | tissue development | regulation of cellular process | regulation of metabolic process | epithelium development | negative regulation of cellular protein catabolic process | spinal cord motor neuron cell fate specification | response to stimulus | vasculature development | embryonic epithelial tube formation | regulation of cellular protein catabolic process | determination of heart left/right asymmetry | spinal cord dorsal/ventral patterning | tube morphogenesis | epithelial tube formation | cardiovascular system development | ventral spinal cord interneuron specification | negative regulation of metabolic process | dorsal/ventral pattern formation | embryo development | blood vessel development | neuron fate commitment | regulation of nucleic acid-templated transcription | system development | ventral spinal cord development | regulation of signal transduction | multicellular organism development | smoothened signaling pathway involved in spinal cord motor neuron cell fate specification | artery development | determination of bilateral symmetry | regulation of gene expression | neural tube closure | embryonic heart tube morphogenesis | coronary vasculature development | animal organ morphogenesis | regulation of nitrogen compound metabolic process | regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning | cytoplasmic sequestering of protein | negative regulation of DNA-binding transcription factor activity | cell fate specification involved in pattern specification | neural tube formation | regulation of transcription by RNA polymerase II | neural tube development | regulation of cellular protein metabolic process | cytoplasmic sequestering of transcription factor | heart looping | skin development | maintenance of protein location | chordate embryonic development | cell communication | ventral spinal cord interneuron differentiation | regulation of cellular metabolic process | regulation of protein metabolic process | heart development | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | cell fate commitment involved in pattern specification | embryonic morphogenesis | neuron differentiation | embryonic organ morphogenesis | ventricular septum development | regionalization | cardiac ventricle development | tissue morphogenesis | regulation of DNA-binding transcription factor activity | embryonic heart tube development | anatomical structure development | cell surface receptor signaling pathway | aorta development | cell fate commitment | smoothened signaling pathway involved in ventral spinal cord interneuron specification | regulation of protein catabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | embryonic organ development | spinal cord patterning | morphogenesis of embryonic epithelium | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | negative regulation of cellular protein metabolic process | smoothened signaling pathway | anatomical structure formation involved in morphogenesis | negative regulation of protein catabolic process | negative regulation of protein metabolic process | cell differentiation in spinal cord | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | smoothened signaling pathway involved in ventral spinal cord patterning | protein localization | anatomical structure morphogenesis | regulation of nervous system development | regulation of developmental process | developmental process | negative regulation of smoothened signaling pathway | cardiac septum development | negative regulation of transcription by RNA polymerase II | tube development | tube closure | cardiac chamber development | tube formation | central nervous system development | spinal cord development | neuron fate specification | circulatory system development | regulation of ubiquitin-dependent protein catabolic process | negative regulation of proteolysis involved in cellular protein catabolic process | signal transduction | regulation of signaling | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | cell projection | cilium | membrane-bounded organelle | nucleus | organelle | intracellular
