QuickView for Slmb;jsessionid=22007B9034255387C1BB67336BA423F2;jsessionid=53270644A38A062D60F71E266F038080 (gene)
- Gene Symbol:
- Btrc
Mus musculus - Full name:
- beta-transducin repeat containing protein
- Synonyms:
- Beta-Trcp1, E3RS-IkappaB, E3RSIkappaB, FWD1, Fbw1a, HOS, Slimb, b-TrCP, beta-TrCP, F-box/WD repeat-containing protein 1A, SCF b-TRCP, btrc
- Genomic Location:
- Chr 19: 45430387-45604503
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
AACTTT_UNKNOWN , AACYNNNNTTCCS_UNKNOWN , ACTAYRNNNCCCR_UNKNOWN , GATA1_03 , GATA_C , RFX1_01 , WHN_B , STAT5A_02 , CRX_Q4 , EFC_Q6
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-10 , Predicted Gene Targets for miR-103 , Predicted Gene Targets for miR-145 , Predicted Gene Targets for miR-15 , Predicted Gene Targets for miR-199 , Predicted Gene Targets for miR-219 , Predicted Gene Targets for miR-224 , Predicted Gene Targets for miR-330 , Predicted Gene Targets for miR-503 , Predicted Gene Targets for miR-496
GO Molecular Function
beta-catenin binding | protein phosphorylated amino acid binding | catalytic activity | ubiquitin-like protein transferase activity | ubiquitin protein ligase activity | phosphoprotein binding | protein binding | protein dimerization activity | ubiquitin-protein transferase activity | transferase activity | ubiquitin-like protein ligase activity
GO Biological Process
positive regulation of circadian rhythm | positive regulation of macromolecule biosynthetic process | protein dephosphorylation | proteolysis | mammary gland duct morphogenesis | morphogenesis of an epithelium | negative regulation of cellular process | negative regulation of RNA biosynthetic process | positive regulation of cellular biosynthetic process | cellular process | organic substance catabolic process | epithelial tube morphogenesis | proteolysis involved in cellular protein catabolic process | negative regulation of nucleic acid-templated transcription | regulation of proteolysis | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | regulation of canonical Wnt signaling pathway | negative regulation of cellular metabolic process | tissue development | regulation of cellular process | regulation of metabolic process | catabolic process | positive regulation of cellular protein metabolic process | epithelium development | mammary gland morphogenesis | response to stimulus | positive regulation of protein metabolic process | regulation of cellular protein catabolic process | gland morphogenesis | tube morphogenesis | protein destabilization | cellular protein catabolic process | rhythmic process | positive regulation of proteolysis | proteasomal protein catabolic process | cellular response to organic cyclic compound | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | protein modification process | macromolecule modification | cell-cell signaling | cell surface receptor signaling pathway involved in cell-cell signaling | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | regulation of signal transduction | Wnt signaling pathway | regulation of protein stability | multicellular organism development | phosphorus metabolic process | mammary gland development | regulation of gene expression | protein catabolic process | positive regulation of cellular metabolic process | animal organ morphogenesis | regulation of nitrogen compound metabolic process | protein modification by small protein conjugation | ubiquitin protein ligase activity | cell proliferation | regulation of cellular protein metabolic process | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process | mammary gland epithelial cell proliferation | phosphate-containing compound metabolic process | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | regulation of RNA metabolic process | proteasome-mediated ubiquitin-dependent protein catabolic process | protein polyubiquitination | protein metabolic process | response to organic substance | gland development | protein ubiquitination | tissue morphogenesis | branching morphogenesis of an epithelial tube | epithelial cell proliferation | regulation of intracellular signal transduction | cellular macromolecule catabolic process | anatomical structure development | cell surface receptor signaling pathway | metabolic process | ubiquitin-protein transferase activity | regulation of protein catabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | regulation of proteasomal protein catabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | protein modification by small protein conjugation or removal | regulation of Wnt signaling pathway | mammary gland epithelium development | morphogenesis of a branching epithelium | ubiquitin-dependent protein catabolic process | organonitrogen compound catabolic process | regulation of cell communication | dephosphorylation | signaling | regulation of transcription, DNA-templated | response to organic cyclic compound | cellular protein metabolic process | morphogenesis of a branching structure | anatomical structure morphogenesis | regulation of circadian rhythm | developmental process | cellular protein modification process | tube development | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of metabolic process | cellular metabolic process | cellular response to organic substance | modification-dependent protein catabolic process | branching involved in mammary gland duct morphogenesis | regulation of I-kappaB kinase/NF-kappaB signaling | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | catalytic complex | cell | cytoplasm | intracellular organelle | ubiquitin ligase complex | protein-containing complex | transferase complex | cullin-RING ubiquitin ligase complex | membrane-bounded organelle | nucleus | organelle | SCF ubiquitin ligase complex | intracellular
