QuickView for Smo;jsessionid=D4105C4D0D68F57DC4925BB7E71ED046;jsessionid=B95F950211AF8CD497E11516699FDAC2 (gene)
- Gene Symbol:
- smo
D. melanogaster - Full name:
- smoothened
- Synonyms:
- CG11561, DmelCG11561, Dmel_CG11561, dSmo, smo, smo, Smo, SMO
- Genomic Location:
- Chr 2L: 277588-282167
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , Macaca mulatta , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: miRecords):
GO Molecular Function
patched binding | transmembrane signaling receptor activity | signaling receptor binding | signaling receptor activity | protein binding | Wnt-activated receptor activity | Wnt-protein binding
GO Biological Process
cell morphogenesis | regulation of cell cycle process | wing disc development | neuron projection morphogenesis | developmental process involved in reproduction | regulation of cellular localization | regulation of localization | regulation of cell cycle G1/S phase transition | morphogenesis of an epithelium | somatic stem cell population maintenance | regulation of programmed cell death | eye development | eye-antennal disc development | negative regulation of cellular process | regulation of protein localization to membrane | cell differentiation | nervous system development | cell part morphogenesis | regulation of G1/S transition of mitotic cell cycle | neurogenesis | post-embryonic animal organ morphogenesis | generation of neurons | pattern specification process | cellular process | cell projection morphogenesis | epithelial tube morphogenesis | imaginal disc morphogenesis | commissural neuron axon guidance | negative regulation of signaling | neuron development | negative regulation of G1/S transition of mitotic cell cycle | canonical Wnt signaling pathway | multicellular organismal reproductive process | stem cell population maintenance | axon guidance | regulation of cell cycle | regulation of smoothened signaling pathway | tissue development | gamete generation | regulation of cellular process | regulation of apoptotic process | epithelium development | cellular component organization | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | eye-antennal disc morphogenesis | response to stimulus | female gamete generation | cell morphogenesis involved in neuron differentiation | regulation of cellular protein localization | regulation of mitotic cell cycle phase transition | metamorphosis | neuron projection guidance | germ cell development | positive regulation of cellular protein localization | tube morphogenesis | regulation of cell cycle phase transition | epithelial cell development | reproduction | wing disc anterior/posterior pattern formation | instar larval or pupal development | anterior/posterior pattern specification, imaginal disc | blastoderm segmentation | G-protein coupled receptor signaling pathway | embryo development | cell-cell signaling | regulation of TOR signaling | cell surface receptor signaling pathway involved in cell-cell signaling | anterior/posterior pattern specification | locomotion | system development | reproductive process | regulation of signal transduction | negative regulation of mitotic cell cycle phase transition | Wnt signaling pathway | post-embryonic animal organ development | multicellular organism development | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | anterior/posterior lineage restriction, imaginal disc | positive regulation of protein localization to plasma membrane | regulation of TORC1 signaling | axon development | animal organ morphogenesis | regulation of Notch signaling pathway | post-embryonic animal morphogenesis | positive regulation of intracellular signal transduction | oogenesis | axonogenesis | non-canonical Wnt signaling pathway | cell morphogenesis involved in differentiation | post-embryonic development | sensory organ development | imaginal disc pattern formation | cell communication | eye morphogenesis | positive regulation of protein localization to membrane | positive regulation of signal transduction | positive regulation of TOR signaling | regulation of mitotic cell cycle | positive regulation of TORC1 signaling | neuron differentiation | multicellular organism reproduction | regionalization | ovarian follicle cell development | tissue morphogenesis | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | cell projection organization | positive regulation of smoothened signaling pathway | regulation of protein localization to plasma membrane | negative regulation of mitotic cell cycle | imaginal disc development | immune response | neuron projection development | maintenance of cell number | animal organ development | smoothened signaling pathway | negative regulation of cell cycle | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | Wnt-activated receptor activity | negative regulation of cell cycle G1/S phase transition | negative regulation of signal transduction | signaling | cell development | anatomical structure morphogenesis | segmentation | developmental process | mucosal immune response | columnar/cuboidal epithelial cell development | tube development | epithelial cell differentiation | central nervous system development | wing disc pattern formation | immune system process | negative regulation of Notch signaling pathway | negative regulation of cell cycle process | regulation of protein localization | regulation of cell death | chemotaxis | sexual reproduction | positive regulation of signaling | signal transduction | regulation of signaling | Bolwig's organ morphogenesis | embryonic pattern specification | multicellular organismal process
GO Cellular Component
integral component of membrane | dendrite | neuron projection | somatodendritic compartment | cytoplasmic vesicle | cell body | cell | neuronal cell body | intrinsic component of membrane | cytoplasm | intracellular organelle | dendritic tree | cell projection | endomembrane system | plasma membrane | cilium | vesicle | integral component of plasma membrane | endosome | membrane-bounded organelle | organelle | cell periphery | axon | intracellular vesicle | intracellular | membrane | intrinsic component of plasma membrane
