QuickView for TCP2;jsessionid=027E8C98AC61FD3317614B88310A0DA0;jsessionid=C4743B6689D56A1FC2FBE0FE38C51412 (gene)

Gene Symbol:

CCT2 Homo sapiens

Full name:

chaperonin containing TCP1 subunit 2

Synonyms:

99D8.1, CCT-beta, CCTB, HEL-S-100n, PRO1633, TCP-1-beta, T-complex protein 1 subunit beta, T-complex protein 1, beta subunit, chaperonin containing TCP1, subunit 2 (beta), chaperonin containing t-complex polypeptide 1, beta subunit, chaperonin containing t-complex polypeptide 1, subunit 2, epididymis secretory sperm binding protein Li 100n

Genomic Location:

Chr 12: 68265475-68281624

Description:

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP...

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The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Two transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Danio rerio ,  Schizosaccharomyces pombe ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

RGAANNTTC_HSF1_01 ,  GGGCGGR_SP1_Q6 ,  ATACTGT_MIR144 ,  CTTTGT_LEF1_Q2

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-144 ,  Predicted Gene Targets for miR-539

Cytogenetic Map:

12q15

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