QuickView for TF;jsessionid=31CC7CF91C1DD0166E3C5786D97C0C21;jsessionid=5BF955B429D4B5D069B98A90A2CBBE81 (gene)
- Gene Symbol:
- Tf
Rattus norvegicus - Full name:
- transferrin
- Synonyms:
- Tfn, Trf, serotransferrin, beta-1 metal-binding globulin, liver regeneration-related protein LRRG03, siderophilin
- Genomic Location:
- Chr 8: 108217774-108244487
- Description:
-
plays a role iin iron transport and homeostasis
- Orthologs:
- Homo sapiens , Mus musculus , Bos taurus , Danio rerio , Gallus gallus , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
transition metal ion transmembrane transporter activity | ferric iron transmembrane transporter activity | guanyl ribonucleotide binding | ferric iron binding | ribonucleoside binding | cation binding | ribonucleotide binding | transmembrane transporter activity | ferrous iron binding | iron chaperone activity | nucleotide binding | iron ion binding | signaling receptor binding | carbohydrate derivative binding | anion binding | cation transmembrane transporter activity | purine nucleotide binding | transporter activity | ion transmembrane transporter activity | ion binding | organic cyclic compound binding | purine nucleoside binding | purine ribonucleoside triphosphate binding | protein binding | iron ion transmembrane transporter activity | metal ion transmembrane transporter activity | GTP binding | metallochaperone activity | transition metal ion binding | transferrin receptor binding | nucleoside binding | inorganic cation transmembrane transporter activity | purine ribonucleotide binding | metal ion binding | heterocyclic compound binding | guanyl nucleotide binding | small molecule binding
GO Biological Process
regulation of JUN kinase activity | SMAD protein signal transduction | transition metal ion transmembrane transporter activity | ferric iron transmembrane transporter activity | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | actin filament-based process | positive regulation of cellular component organization | regulation of neurogenesis | iron ion transmembrane transport | intracellular signal transduction | regulation of cell development | regulation of localization | actin cytoskeleton organization | establishment of localization | response to hormone | myeloid cell differentiation | positive regulation of developmental process | regulation of MAP kinase activity | response to metal ion | cell differentiation | defense response | nervous system development | cellular chemical homeostasis | neurogenesis | cellular response to iron ion | positive regulation of phosphate metabolic process | positive regulation of cellular component movement | generation of neurons | regulation of bone remodeling | response to organophosphorus | positive regulation of neurological system process | positive regulation of cellular biosynthetic process | cellular process | regulation of cell motility | localization | cellular homeostasis | metal ion transport | immune system development | positive regulation of protein kinase activity | transition metal ion transport | response to hypoxia | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | response to inorganic substance | regulation of neurological system process | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | positive regulation of stress-activated MAPK cascade | transmembrane transporter activity | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | cellular component organization | positive regulation of myelination | MAPK cascade | regulation of iron ion import | cellular response to metal ion | positive regulation of stress-activated protein kinase signaling cascade | response to stimulus | JNK cascade | positive regulation of protein metabolic process | signal transduction by protein phosphorylation | regulation of oligodendrocyte progenitor proliferation | response to stress | regulation of cell proliferation | programmed cell death | supramolecular fiber organization | cellular response to inorganic substance | positive regulation of gliogenesis | cellular response to organic cyclic compound | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | hemopoiesis | protein modification process | response to iron ion | macromolecule modification | activation of protein kinase activity | metal ion homeostasis | stress-activated protein kinase signaling cascade | regulation of nucleic acid-templated transcription | leukocyte differentiation | regulation of cellular response to stress | response to nitrogen compound | apoptotic process | cellular response to hormone stimulus | system development | response to oxygen levels | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | regulation of MAPK cascade | phosphorus metabolic process | response to purine-containing compound | actin filament organization | response to follicle-stimulating hormone | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | ion transmembrane transport | regulation of receptor-mediated endocytosis | positive regulation of receptor-mediated endocytosis | regulation of gene expression | osteoclast differentiation | cellular response to stress | cation transmembrane transporter activity | cellular response to gonadotropin stimulus | myeloid leukocyte differentiation | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | regulation of myelination | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | positive regulation of JNK cascade | positive regulation of intracellular signal transduction | regulation of cellular component movement | ion transmembrane transporter activity | positive regulation of cell differentiation | acute-phase response | stress-activated MAPK cascade | regulation of cellular protein metabolic process | phosphorylation | protein phosphorylation | cation homeostasis | phosphate-containing compound metabolic process | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | transmembrane receptor protein serine/threonine kinase signaling pathway | inflammatory response | regulation of protein metabolic process | positive regulation of signal transduction | ferric iron transport | homeostatic process | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of locomotion | iron ion homeostasis | regulation of RNA metabolic process | positive regulation of transport | positive regulation of molecular function | activation of MAPK activity | cation transmembrane transport | protein metabolic process | iron ion transmembrane transporter activity | positive regulation of protein modification process | response to organic substance | regulation of kinase activity | metal ion transmembrane transporter activity | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | positive regulation of neurogenesis | regulation of neural precursor cell proliferation | metabolic process | positive regulation of cell development | regulation of RNA biosynthetic process | regulation of bone resorption | regulation of tissue remodeling | regulation of vesicle-mediated transport | chemical homeostasis | organic substance metabolic process | cell death | animal organ development | positive regulation of kinase activity | ion homeostasis | cellular response to cAMP | regulation of phosphate metabolic process | cytoskeleton organization | inorganic cation transmembrane transport | cellular iron ion homeostasis | response to gonadotropin | regulation of JNK cascade | response to cAMP | positive regulation of MAPK cascade | cellular response to follicle-stimulating hormone stimulus | regulation of stress-activated MAPK cascade | regulation of cell communication | regulation of gliogenesis | transmembrane transport | signaling | positive regulation of oligodendrocyte progenitor proliferation | inorganic cation transmembrane transporter activity | regulation of transcription, DNA-templated | response to organic cyclic compound | regulation of endocytosis | positive regulation of phosphorylation | cellular protein metabolic process | cation transport | positive regulation of MAP kinase activity | iron ion transport | positive regulation of tissue remodeling | regulation of nervous system development | regulation of developmental process | regulation of ion transport | positive regulation of neural precursor cell proliferation | developmental process | organelle organization | cellular protein modification process | regulation of transport | positive regulation of transcription, DNA-templated | positive regulation of bone resorption | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | cellular metal ion homeostasis | ERK1 and ERK2 cascade | response to lead ion | positive regulation of JUN kinase activity | positive regulation of metabolic process | ion transport | transition metal ion homeostasis | acute inflammatory response | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | cellular response to organic substance | activation of JUN kinase activity | positive regulation of cell motility | positive regulation of endocytosis | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | basal plasma membrane | late endosome | apical plasma membrane | extrinsic component of membrane | extracellular matrix | basement membrane | cytoplasmic vesicle | basal part of cell | cell | plasma membrane protein complex | extrinsic component of plasma membrane | HFE-transferrin receptor complex | intrinsic component of membrane | external side of plasma membrane | cytoplasm | collagen-containing extracellular matrix | intracellular organelle | receptor complex | apical part of cell | protein-containing complex | recycling endosome | endomembrane system | plasma membrane | vesicle | perinuclear region of cytoplasm | clathrin-coated pit | endosome | extracellular region | membrane-bounded organelle | organelle | extracellular space | cell periphery | extrinsic component of external side of plasma membrane | early endosome | basolateral plasma membrane | intracellular vesicle | cell surface | cell tip | endocytic vesicle | intracellular | membrane
