QuickView for TFAP2A;jsessionid=8D8FEBECFBE421F4B78766D0056CBB5A;jsessionid=E6523FB6F7A713BEDBB3E7C62BB5BF69 (gene)

Gene Symbol:

Tfap2a Mus musculus

Full name:

transcription factor AP-2, alpha

Synonyms:

AP-2, AP2alpha, Ap-2 (a), Ap2, Ap2tf, Tcfap2a, transcription factor AP-2-alpha, activating enhancer-binding protein 2 alpha, activator protein 2

Genomic Location:

Chr 13: 40812101-40830289

Description:

This gene is a member of the activator protein 2 (AP-2) transcription factor family. The protein encoded by this gene can act as both an activator and repressor of gene transcription, and plays an important role in early embryogenesis, specifically in cranial development. This protein forms both homodimers and heterodimers, and binds to a GC-rich c...

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This gene is a member of the activator protein 2 (AP-2) transcription factor family. The protein encoded by this gene can act as both an activator and repressor of gene transcription, and plays an important role in early embryogenesis, specifically in cranial development. This protein forms both homodimers and heterodimers, and binds to a GC-rich consensus sequence found in some promoters and enhancers. Disruption of this gene causes perinatal death, with neural tube, craniofacial, and limb mesenchyme defects. Alternative splicing results in multiple transcript variants that encode multiple protein isoforms.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AACTTT_UNKNOWN ,  MYOGNF1_01 ,  E47_02 ,  IK1_01 ,  IK2_01 ,  IK3_01 ,  AREB6_01 ,  MEIS1AHOXA9_01 ,  LHX3_01 ,  PTF1BETA_Q6 ,  CACCCBINDINGFACTOR_Q6 ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  RRAGTTGT_UNKNOWN ,  WGTTNNNNNAAA_UNKNOWN ,  CAGGTA_AREB6_01 ,  TAATTA_CHX10_01 ,  CAGGTG_E12_Q6 ,  TTGTTT_FOXO4_01 ,  CTTTGT_LEF1_Q2 ,  YTAATTAA_LHX3_01 ,  YTATTTTNR_MEF2_02 ,  TATAAA_TATA_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-15

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