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QuickView for TLR2;jsessionid=27313DECEF4B44226D557A14E184921F;jsessionid=8ADCCCC6853B3F0E08BCD3E52918FE65 (gene)


Gene Symbol:
TLR2 Canis lupus familiaris Canis lupus familiaris
Full name:
toll-like receptor 2
Synonyms:
N/A
Genomic Location:
Chr 15: 54484397-54486909
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Bos taurus Gallus gallus Danio rerio Pan troglodytes
External Links:
Entrez Gene


Transcripts Names
NM_001005264
Protein Names
C0IRA0



GO Molecular Function

peptide binding | amyloid-beta binding | protein-containing complex binding | lipid binding | signaling receptor binding | carbohydrate derivative binding | Toll-like receptor binding | amide binding | signaling receptor activity | identical protein binding | protein heterodimerization activity | lipopeptide binding | signaling pattern recognition receptor activity | protein binding | peptidoglycan binding | protein dimerization activity | lipopolysaccharide binding | glycosaminoglycan binding | triacyl lipopeptide binding

GO Biological Process

positive regulation of immune response | detection of diacyl bacterial lipopeptide | detection of stimulus | response to cytokine | immune response-regulating signaling pathway | intracellular signal transduction | cellular response to diacyl bacterial lipopeptide | regulation of localization | positive regulation of DNA-binding transcription factor activity | toll-like receptor 2 signaling pathway | defense response to other organism | establishment of localization | regulation of immune system process | defense response | positive regulation of protein secretion | innate immune response-activating signal transduction | cellular process | secretion | toll-like receptor signaling pathway | localization | cellular response to bacterial lipopeptide | protein transport | I-kappaB phosphorylation | macromolecule localization | regulation of response to cytokine stimulus | positive regulation of interleukin-8 production | regulation of immune response | regulation of cellular process | regulation of metabolic process | cellular response to molecule of bacterial origin | detection of triacyl bacterial lipopeptide | cellular response to interferon-gamma | regulation of peptide secretion | cellular response to triacyl bacterial lipopeptide | response to stimulus | positive regulation of NIK/NF-kappaB signaling | regulation of interleukin-8 secretion | positive regulation of innate immune response | positive regulation of immune system process | response to stress | activation of innate immune response | secretion by cell | positive regulation of cytokine secretion | response to molecule of bacterial origin | immune response-activating signal transduction | regulation of protein transport | protein modification process | regulation of peptide transport | macromolecule modification | regulation of nucleic acid-templated transcription | positive regulation of peptide secretion | positive regulation of response to cytokine stimulus | response to external biotic stimulus | detection of molecule of bacterial origin | nitrogen compound metabolic process | regulation of signal transduction | detection of chemical stimulus | pattern recognition receptor signaling pathway | regulation of toll-like receptor signaling pathway | phosphorus metabolic process | positive regulation of inflammatory response | regulation of gene expression | positive regulation of secretion | organic substance transport | regulation of nitrogen compound metabolic process | peptide transport | positive regulation of intracellular signal transduction | cellular response to cytokine stimulus | phosphorylation | positive regulation of chemokine production | interleukin-10 production | cytokine production involved in immune response | protein phosphorylation | phosphate-containing compound metabolic process | response to bacterium | peptide secretion | cell communication | regulation of cellular metabolic process | signaling pattern recognition receptor activity | inflammatory response | regulation of NIK/NF-kappaB signaling | positive regulation of signal transduction | defense response to bacterium | positive regulation of establishment of protein localization | detection of bacterial lipoprotein | regulation of RNA metabolic process | positive regulation of transport | cytokine secretion involved in immune response | positive regulation of molecular function | regulation of cytokine secretion | cytokine production | activation of immune response | protein metabolic process | regulation of establishment of protein localization | response to organic substance | regulation of innate immune response | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | cellular response to lipoteichoic acid | metabolic process | cytokine secretion | regulation of RNA biosynthetic process | amide transport | regulation of secretion | positive regulation of interleukin-6 production | immune response | positive regulation of interleukin-8 secretion | organic substance metabolic process | response to bacterial lipoprotein | positive regulation of NF-kappaB transcription factor activity | regulation of protein secretion | detection of bacterium | regulation of Wnt signaling pathway | establishment of protein localization | response to interferon-gamma | positive regulation of cytokine production | cell activation | positive regulation of protein transport | defense response to Gram-positive bacterium | regulation of cell communication | signaling | regulation of transcription, DNA-templated | I-kappaB kinase/NF-kappaB signaling | positive regulation of cellular response to macrophage colony-stimulating factor stimulus | protein localization | cellular protein metabolic process | regulation of cytokine production | response to biotic stimulus | detection of biotic stimulus | cellular protein modification process | regulation of chemokine production | regulation of transport | innate immune response | MyD88-dependent toll-like receptor signaling pathway | positive regulation of metabolic process | immune system process | positive regulation of Wnt signaling pathway | cellular metabolic process | cellular response to organic substance | regulation of protein localization | protein secretion | regulation of interleukin-6 production | regulation of inflammatory response | positive regulation of toll-like receptor signaling pathway | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

integral component of membrane | intracellular membrane-bounded organelle | endocytic vesicle membrane | organelle membrane | cytoplasmic vesicle | Toll-like receptor 1-Toll-like receptor 2 protein complex | cell | plasma membrane protein complex | intrinsic component of membrane | cytoplasm | intracellular organelle | receptor complex | membrane microdomain | Golgi apparatus | protein-containing complex | phagocytic vesicle membrane | endomembrane system | plasma membrane | membrane raft | vesicle | membrane-bounded organelle | organelle | vesicle membrane | cell periphery | intracellular vesicle | cell surface | endocytic vesicle | intracellular | membrane | cytoplasmic vesicle membrane | intrinsic component of plasma membrane | phagocytic vesicle