QuickView for TLR2;jsessionid=27313DECEF4B44226D557A14E184921F;jsessionid=627B97D8E5C92E9110C1CC9E78016152 (gene)
- Gene Symbol:
- Tlr2
Rattus norvegicus - Full name:
- toll-like receptor 2
- Synonyms:
- toll-like receptor 2, toll-like receptor 2 variant 1, toll-like receptor 2 variant 2
- Genomic Location:
- Chr 2: 175607990-175613992
- Description:
-
receptor for whom the bell...; involved in the response to bacteria and injury
- Orthologs:
- Homo sapiens , Mus musculus , D. melanogaster , Macaca mulatta , Bos taurus , Gallus gallus , Danio rerio , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
GO Molecular Function
peptide binding | amyloid-beta binding | diacyl lipopeptide binding | lipoteichoic acid binding | protein-containing complex binding | lipid binding | signaling receptor binding | carbohydrate derivative binding | Toll-like receptor binding | amide binding | signaling receptor activity | identical protein binding | protein heterodimerization activity | lipopeptide binding | signaling pattern recognition receptor activity | protein binding | peptidoglycan binding | protein dimerization activity | lipopolysaccharide binding | glycosaminoglycan binding | triacyl lipopeptide binding
GO Biological Process
positive regulation of immune response | regulation of ERK1 and ERK2 cascade | regulation of supramolecular fiber organization | positive regulation of macrophage cytokine production | regulation of interleukin-1 beta production | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | detection of diacyl bacterial lipopeptide | detection of stimulus | response to cytokine | leukotriene metabolic process | regulation of neurogenesis | immune response-regulating signaling pathway | response to lipopolysaccharide | intracellular signal transduction | regulation of synapse assembly | cellular response to diacyl bacterial lipopeptide | regulation of cell development | regulation of localization | positive regulation of DNA-binding transcription factor activity | toll-like receptor 2 signaling pathway | negative regulation of phagocytosis | defense response to other organism | establishment of localization | immune response-regulating cell surface receptor signaling pathway | regulation of autophagy | regulation of immune system process | response to hormone | myeloid cell differentiation | regulation of nitric oxide biosynthetic process | negative regulation of cellular process | positive regulation of developmental process | cell differentiation | immune response-activating cell surface receptor signaling pathway | negative regulation of growth of symbiont involved in interaction with host | defense response | nervous system development | response to drug | reactive oxygen species metabolic process | neurogenesis | positive regulation of interleukin-1 beta secretion | positive regulation of phosphate metabolic process | regulation of organelle organization | positive regulation of cellular component movement | regulation of actin polymerization or depolymerization | polyol transport | generation of neurons | positive regulation of protein secretion | innate immune response activating cell surface receptor signaling pathway | innate immune response-activating signal transduction | positive regulation of cellular biosynthetic process | cellular process | secretion | toll-like receptor signaling pathway | regulation of cytokine biosynthetic process | regulation of cell motility | localization | cellular response to bacterial lipopeptide | axon ensheathment | protein transport | positive regulation of immune effector process | negative regulation of synapse organization | positive regulation of reactive oxygen species metabolic process | response to progesterone | I-kappaB phosphorylation | immune system development | learning | macromolecule localization | regulation of response to cytokine stimulus | response to hypoxia | positive regulation of nitrogen compound metabolic process | myeloid cell development | central nervous system myelination | response to peptide hormone | regulation of cell differentiation | interspecies interaction between organisms | regulation of interferon-beta production | positive regulation of interleukin-8 production | regulation of immune response | regulation of cellular process | leukocyte activation | regulation of metabolic process | chloramphenicol transport | gliogenesis | regulation of protein complex assembly | cellular response to molecule of bacterial origin | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | central nervous system myelin formation | cellular component organization | detection of triacyl bacterial lipopeptide | cellular response to interferon-gamma | regulation of actin filament length | positive regulation of tumor necrosis factor production | regulation of peptide secretion | regulation of type I interferon production | cellular response to triacyl bacterial lipopeptide | response to stimulus | positive regulation of interleukin-1 beta production | positive regulation of NIK/NF-kappaB signaling | regulation of interleukin-8 secretion | positive regulation of innate immune response | oligodendrocyte development | positive regulation of nitric oxide metabolic process | positive regulation of immune system process | cellular response to peptidoglycan | positive regulation of protein metabolic process | response to stress | regulation of cell proliferation | response to peptide | ensheathment of neurons | axon ensheathment in central nervous system | tumor necrosis factor production | positive regulation of cytokine biosynthetic process | activation of innate immune response | positive regulation of interleukin-18 production | secretion by cell | organic hydroxy compound transport | positive regulation of cytokine secretion | response to molecule of bacterial origin | macrophage differentiation | immune response-activating signal transduction | regulation of macroautophagy | negative regulation of transport | positive regulation of gliogenesis | regulation of phagocytosis | regulation of protein transport | regulation of cellular component size | positive regulation of RNA biosynthetic process | hemopoiesis | cellular component assembly | protein modification process | regulation of synapse structure or activity | regulation of peptide transport | macromolecule modification | regulation of oligodendrocyte differentiation | regulation of nucleic acid-templated transcription | positive regulation of peptide secretion | leukocyte differentiation | induction by symbiont of defense-related host nitric oxide production | regulation of neurotransmitter levels | positive regulation of response to cytokine stimulus | response to nitrogen compound | positive regulation of reactive oxygen species biosynthetic process | response to external biotic stimulus | system development | detection of molecule of bacterial origin | response to oxygen levels | nitrogen compound metabolic process | regulation of signal transduction | detection of chemical stimulus | pattern recognition receptor signaling pathway | negative regulation of growth | myelination | regulation of actin cytoskeleton organization | multicellular organism development | regulation of toll-like receptor signaling pathway | positive regulation of tumor necrosis factor secretion | regulation of MAPK cascade | phosphorus metabolic process | regulation of actin filament organization | positive regulation of inflammatory response | learning or memory | response to fatty acid | regulation of phosphorylation | regulation of gene expression | positive regulation of secretion | organic substance transport | response to ketone | response to lipid | nervous system process | myeloid leukocyte differentiation | modification of morphology or physiology of other organism | negative regulation of cytokine production | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | negative regulation of actin filament polymerization | response to peptidoglycan | regulation of synapse organization | regulation of nitrogen compound metabolic process | regulation of cell migration | small molecule metabolic process | positive regulation of interleukin-12 production | peptide transport | positive regulation of intracellular signal transduction | regulation of cellular component movement | regulation of transcription by RNA polymerase II | negative regulation of interleukin-17 production | positive regulation of cell differentiation | cognition | neurotransmitter metabolic process | positive regulation of cell migration | cellular response to cytokine stimulus | negative regulation of interleukin-12 production | regulation of cellular protein metabolic process | glial cell differentiation | phosphorylation | positive regulation of interleukin-1 secretion | positive regulation of chemokine production | response to toxic substance | microglial cell activation | interleukin-10 production | cytokine production involved in immune response | protein phosphorylation | regulation of tumor necrosis factor production | regulation of leukocyte migration | phosphate-containing compound metabolic process | response to bacterium | response to fungus | regulation of interleukin-1 production | peptide secretion | cell communication | regulation of cellular metabolic process | regulation of actin filament polymerization | positive regulation of interleukin-1 production | signaling pattern recognition receptor activity | inflammatory response | regulation of cytokine production involved in immune response | regulation of NIK/NF-kappaB signaling | regulation of protein metabolic process | positive regulation of signal transduction | defense response to bacterium | positive regulation of establishment of protein localization | regulation of protein phosphorylation | detection of bacterial lipoprotein | regulation of locomotion | regulation of RNA metabolic process | positive regulation of transport | cytokine secretion involved in immune response | drug metabolic process | carboxylic acid metabolic process | positive regulation of molecular function | regulation of cytokine secretion | cytokine production | positive regulation of myeloid leukocyte cytokine production involved in immune response | reactive nitrogen species metabolic process | activation of immune response | response to molecule of fungal origin | protein metabolic process | regulation of establishment of protein localization | negative regulation of protein polymerization | positive regulation of protein modification process | regulation of growth | response to organic substance | regulation of innate immune response | positive regulation of xenophagy | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | cellular response to lipoteichoic acid | response to insulin | cell surface pattern recognition receptor signaling pathway | anatomical structure development | cell surface receptor signaling pathway | positive regulation of neurogenesis | negative regulation of endocytosis | metabolic process | positive regulation of cell development | cytokine secretion | negative regulation of growth of symbiont in host | regulation of interleukin-1 beta secretion | regulation of RNA biosynthetic process | negative regulation of cytoskeleton organization | positive regulation of cytokine production involved in immune response | oligodendrocyte differentiation | positive regulation of glial cell differentiation | amide transport | regulation of vesicle-mediated transport | regulation of secretion | behavior | positive regulation of interleukin-6 production | macrophage activation | immune response | positive regulation of interleukin-8 secretion | negative regulation of protein complex assembly | organic substance metabolic process | regulation of tumor necrosis factor biosynthetic process | response to bacterial lipoprotein | animal organ development | positive regulation of NF-kappaB transcription factor activity | regulation of protein secretion | positive regulation of leukocyte migration | positive regulation of ERK1 and ERK2 cascade | detection of bacterium | regulation of tumor necrosis factor secretion | regulation of Wnt signaling pathway | regulation of phosphate metabolic process | regulation of dendritic cell cytokine production | positive regulation of autophagy | establishment of protein localization | response to interferon-gamma | positive regulation of cytokine production | positive regulation of macroautophagy | cell activation | positive regulation of MAPK cascade | drug transport | positive regulation of protein transport | regulation of reactive oxygen species biosynthetic process | anatomical structure formation involved in morphogenesis | icosanoid metabolic process | regulation of glial cell differentiation | response to defense-related host nitric oxide production | defense response to Gram-positive bacterium | regulation of cell communication | positive regulation of interleukin-10 production | regulation of gliogenesis | signaling | regulation of transcription, DNA-templated | glial cell development | response to organic cyclic compound | cell development | regulation of endocytosis | I-kappaB kinase/NF-kappaB signaling | positive regulation of cellular response to macrophage colony-stimulating factor stimulus | protein localization | organic acid metabolic process | positive regulation of phosphorylation | cellular protein metabolic process | regulation of cytokine production | anatomical structure morphogenesis | response to biotic stimulus | regulation of nervous system development | regulation of developmental process | positive regulation of tumor necrosis factor biosynthetic process | detection of biotic stimulus | developmental process | microglia development | nitric oxide metabolic process | cellular protein modification process | myelin assembly | regulation of chemokine production | positive regulation of oligodendrocyte differentiation | regulation of transport | positive regulation of transcription, DNA-templated | regulation of reactive oxygen species metabolic process | negative regulation of cell proliferation | innate immune response | MyD88-dependent toll-like receptor signaling pathway | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | positive regulation of transcription by RNA polymerase II | negative regulation of supramolecular fiber organization | positive regulation of nitric oxide biosynthetic process | central nervous system development | positive regulation of metabolic process | regulation of actin filament-based process | antibiotic transport | immune system process | positive regulation of Wnt signaling pathway | cellular metabolic process | hematopoietic or lymphoid organ development | cellular response to organic substance | regulation of protein localization | protein secretion | positive regulation of cell motility | positive regulation of type I interferon production | response to steroid hormone | regulation of interleukin-6 production | regulation of inflammatory response | negative regulation of synapse assembly | regulation of cellular component organization | regulation of cytoskeleton organization | positive regulation of toll-like receptor signaling pathway | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of nitric-oxide synthase biosynthetic process | positive regulation of gene expression | macromolecule metabolic process | positive regulation of interferon-beta production | multicellular organismal process | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | cell body | Toll-like receptor 1-Toll-like receptor 2 protein complex | cell | plasma membrane protein complex | intrinsic component of membrane | external side of plasma membrane | cytoplasm | intracellular organelle | receptor complex | membrane microdomain | Golgi apparatus | protein-containing complex | cell projection | endomembrane system | plasma membrane | membrane raft | Toll-like receptor 2-Toll-like receptor 6 protein complex | integral component of plasma membrane | membrane-bounded organelle | organelle | cell periphery | cell surface | intracellular | membrane | intrinsic component of plasma membrane
