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QuickView for TLR9;jsessionid=B82660C14D76B0B1CB11A3136AEDDA6B;jsessionid=6ACABE3DEF2CD02B42614653715568F3 (gene)


Gene Symbol:
Tlr9 Mus musculus Mus musculus
Full name:
toll-like receptor 9
Synonyms:
toll-like receptor 9
Genomic Location:
Chr 9: 106124929-106129207
Orthologs:
Homo sapiens Rattus norvegicus Macaca mulatta Bos taurus Danio rerio Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene


Transcripts Names
NM_031178



GO Molecular Function

sequence-specific DNA binding | transmembrane signaling receptor activity | nucleic acid binding | signaling receptor binding | unmethylated CpG binding | cytokine receptor binding | DNA binding | signaling receptor activity | siRNA binding | organic cyclic compound binding | signaling pattern recognition receptor activity | protein binding | interleukin-1 receptor binding | growth factor receptor binding | heterocyclic compound binding | RNA binding

GO Biological Process

positive regulation of immune response | regulation of JUN kinase activity | positive regulation of macromolecule biosynthetic process | response to virus | negative regulation of immune system process | regulation of B cell activation | immune response-regulating signaling pathway | intracellular signal transduction | regulation of localization | positive regulation of DNA-binding transcription factor activity | defense response to other organism | regulation of autophagy | regulation of immune system process | negative regulation of cellular process | regulation of MAP kinase activity | epithelial structure maintenance | positive regulation of lymphocyte activation | regulation of interferon-beta biosynthetic process | defense response | response to drug | positive regulation of phosphate metabolic process | response to antibiotic | tissue homeostasis | defense response to Gram-negative bacterium | innate immune response-activating signal transduction | positive regulation of cellular biosynthetic process | cellular process | toll-like receptor signaling pathway | regulation of cytokine biosynthetic process | negative regulation of signaling | positive regulation of immune effector process | I-kappaB phosphorylation | positive regulation of protein kinase activity | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | positive regulation of interferon-gamma biosynthetic process | regulation of cell differentiation | anatomical structure homeostasis | regulation of interferon-beta production | positive regulation of interleukin-8 production | positive regulation of granulocyte macrophage colony-stimulating factor production | regulation of immune response | regulation of cellular process | leukocyte activation | regulation of metabolic process | positive regulation of stress-activated MAPK cascade | positive regulation of interferon-gamma production | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | negative regulation of toll-like receptor signaling pathway | positive regulation of tumor necrosis factor production | regulation of peptide secretion | regulation of type I interferon production | positive regulation of stress-activated protein kinase signaling cascade | response to stimulus | positive regulation of NIK/NF-kappaB signaling | positive regulation of innate immune response | positive regulation of immune system process | positive regulation of protein metabolic process | positive regulation of immunoglobulin production | response to stress | regulation of ATPase activity | positive regulation of lymphocyte proliferation | regulation of cell proliferation | multicellular organismal homeostasis | positive regulation of B cell proliferation | tumor necrosis factor production | positive regulation of cytokine biosynthetic process | positive regulation of cell activation | activation of innate immune response | negative regulation of transporter activity | positive regulation of interleukin-18 production | response to molecule of bacterial origin | immune response-activating signal transduction | negative regulation of transport | cellular response to organic cyclic compound | regulation of protein transport | positive regulation of protein serine/threonine kinase activity | positive regulation of RNA biosynthetic process | protein modification process | regulation of peptide transport | macromolecule modification | negative regulation of calcium ion transmembrane transport | negative regulation of transmembrane transport | regulation of lymphocyte differentiation | regulation of nucleic acid-templated transcription | negative regulation of NF-kappaB transcription factor activity | regulation of cellular response to stress | response to nitrogen compound | positive regulation of mononuclear cell proliferation | response to external biotic stimulus | nitrogen compound metabolic process | regulation of signal transduction | pattern recognition receptor signaling pathway | regulation of interleukin-8 biosynthetic process | cellular response to antibiotic | negative regulation of interleukin-6 production | negative regulation of catalytic activity | regulation of toll-like receptor signaling pathway | regulation of MAPK cascade | phosphorus metabolic process | positive regulation of inflammatory response | maintenance of gastrointestinal epithelium | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | regulation of gene expression | negative regulation of cytokine production | positive regulation of cellular metabolic process | defense response to virus | positive regulation of protein phosphorylation | digestive system process | regulation of lymphocyte activation | regulation of nitrogen compound metabolic process | positive regulation of JNK cascade | positive regulation of interleukin-12 production | negative regulation of DNA-binding transcription factor activity | positive regulation of intracellular signal transduction | regulation of transcription by RNA polymerase II | negative regulation of ion transmembrane transport | negative regulation of calcium ion transmembrane transporter activity | regulation of cellular protein metabolic process | phosphorylation | negative regulation of ion transport | negative regulation of calcium-transporting ATPase activity | regulation of calcium ion transmembrane transport | positive regulation of chemokine production | microglial cell activation | protein phosphorylation | regulation of tumor necrosis factor production | phosphate-containing compound metabolic process | cellular response to drug | response to bacterium | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | positive regulation of interferon-beta biosynthetic process | signaling pattern recognition receptor activity | inflammatory response | negative regulation of calcium ion transport | regulation of cytokine production involved in immune response | regulation of NIK/NF-kappaB signaling | regulation of protein metabolic process | positive regulation of signal transduction | defense response to bacterium | homeostatic process | positive regulation of cell proliferation | regulation of protein phosphorylation | regulation of RNA metabolic process | positive regulation of B cell activation | positive regulation of interferon-alpha production | positive regulation of molecular function | regulation of cytokine secretion | cytokine production | toll-like receptor 9 signaling pathway | activation of immune response | protein metabolic process | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | regulation of innate immune response | negative regulation of ATPase activity | regulation of hemopoiesis | regulation of kinase activity | response to chloroquine | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | metabolic process | regulation of RNA biosynthetic process | positive regulation of leukocyte activation | regulation of secretion | positive regulation of toll-like receptor 9 signaling pathway | positive regulation of interleukin-6 production | macrophage activation | immune response | negative regulation of ion transmembrane transporter activity | organic substance metabolic process | regulation of B cell differentiation | regulation of cell activation | positive regulation of NF-kappaB transcription factor activity | regulation of protein secretion | positive regulation of kinase activity | regulation of phosphate metabolic process | regulation of ion transmembrane transport | regulation of dendritic cell cytokine production | positive regulation of autophagy | negative regulation of interleukin-8 production | positive regulation of cytokine production | regulation of JNK cascade | cell activation | positive regulation of MAPK cascade | regulation of stress-activated MAPK cascade | regulation of cell communication | positive regulation of interleukin-10 production | negative regulation of molecular function | negative regulation of signal transduction | signaling | positive regulation of I-kappaB kinase/NF-kappaB signaling | regulation of immunoglobulin production | regulation of transcription, DNA-templated | response to organic cyclic compound | I-kappaB kinase/NF-kappaB signaling | regulation of transmembrane transporter activity | regulation of ion transmembrane transporter activity | positive regulation of phosphorylation | cellular protein metabolic process | regulation of cytokine production | positive regulation of MAP kinase activity | response to biotic stimulus | regulation of developmental process | regulation of ion transport | regulation of calcium ion transport | cellular protein modification process | digestion | regulation of calcium-transporting ATPase activity | regulation of toll-like receptor 9 signaling pathway | regulation of chemokine production | regulation of transport | cellular response to chloroquine | positive regulation of transcription, DNA-templated | regulation of B cell proliferation | innate immune response | MyD88-dependent toll-like receptor signaling pathway | positive regulation of nucleic acid-templated transcription | response to organonitrogen compound | positive regulation of transcription by RNA polymerase II | positive regulation of interferon-alpha biosynthetic process | negative regulation of hydrolase activity | positive regulation of JUN kinase activity | positive regulation of metabolic process | positive regulation of interleukin-8 biosynthetic process | regulation of calcium ion transmembrane transporter activity | regulation of interferon-gamma production | immune system process | cellular metabolic process | cellular response to organic substance | regulation of protein localization | positive regulation of type I interferon production | regulation of interleukin-6 production | regulation of inflammatory response | regulation of I-kappaB kinase/NF-kappaB signaling | positive regulation of toll-like receptor signaling pathway | response to other organism | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of nitric-oxide synthase biosynthetic process | positive regulation of gene expression | macromolecule metabolic process | positive regulation of interferon-beta production | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | endolysosome | intracellular membrane-bounded organelle | apical plasma membrane | cytoplasmic vesicle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | apical part of cell | endomembrane system | plasma membrane | vacuole | vesicle | lytic vacuole | endosome | membrane-bounded organelle | organelle | lysosome | cell periphery | basolateral plasma membrane | early phagosome | intracellular vesicle | endocytic vesicle | intracellular | membrane | phagocytic vesicle