QuickView for TMPRSS4;jsessionid=C210137F7A534C989ADEB8B5630AB928;jsessionid=DE35A79C97009E6B4E3389ADFE714075;jsessionid=D828FE4183F18CEA58B5699263E980F3;jsessionid=DEB7C657AA931B2E5314816984A4452A (gene)

Gene Symbol:

TMPRSS4 Homo sapiens

Full name:

transmembrane protease, serine 4

Synonyms:

CAPH2, MT-SP2, TMPRSS3, transmembrane protease serine 4, channel-activating protease 2, membrane-type serine protease 2, transmembrane serine protease 3, type II membrane serine protease

Genomic Location:

Chr 11: 117452937-117495768

Description:

This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and...

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This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TEF1_Q6 ,  CAGGTG_E12_Q6 ,  CEBPB_02

Cytogenetic Map:

11q23.3

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