QuickView for TNDM2;jsessionid=D240C0E6F6FC9830BE675992B75D63B4;jsessionid=27357955DDF6F2CEE2290ED31702F6D6 (gene)
- Gene Symbol:
- Abcc8
Rattus norvegicus - Full name:
- ATP binding cassette subfamily C member 8
- Synonyms:
- Sur, Sur1, ATP-binding cassette sub-family C member 8, ATP-binding cassette transporter sub-family C member 8, ATP-binding cassette, sub-family C (CFTR/MRP), member 8, ATP-binding cassette, subfamily C (CFTR/MRP), member 8, sulfonylurea receptor 1, sulphonylurea receptor 1
- Genomic Location:
- Chr 1: 96622480-96703769
- Description:
-
binds sulfonylurea; subunit of the ATP-sensitive potassium channel K(ATP), which is composed of Sur1 and the inwardly rectifying K(+) channel subunit, Kir6.2
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
ATPase activity, coupled to transmembrane movement of substances | passive transmembrane transporter activity | transmembrane signaling receptor activity | ribonucleotide binding | transmembrane transporter activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | catalytic activity | ion channel binding | ATP binding | anion binding | adenyl nucleotide binding | sulfonylurea receptor activity | nucleoside-triphosphatase activity | cation transmembrane transporter activity | ATPase activity, coupled | signaling receptor activity | active transmembrane transporter activity | purine nucleotide binding | transporter activity | ion transmembrane transporter activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | potassium channel activity | metal ion transmembrane transporter activity | potassium ion transmembrane transporter activity | hydrolase activity, acting on acid anhydrides | cation channel activity | inorganic cation transmembrane transporter activity | purine ribonucleotide binding | monovalent inorganic cation transmembrane transporter activity | adenyl ribonucleotide binding | channel activity | drug binding | ion channel activity | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | substrate-specific channel activity | small molecule binding
GO Biological Process
response to radiation | regulation of muscle system process | negative regulation of neuroblast migration | positive regulation of cellular component organization | regulation of neurogenesis | positive regulation of ion transmembrane transporter activity | response to lipopolysaccharide | negative regulation of peptide secretion | regulation of cell development | regulation of localization | ATPase activity, coupled to transmembrane movement of substances | negative regulation of glial cell proliferation | establishment of localization | response to hormone | negative regulation of cellular process | response to metal ion | cell differentiation | nervous system development | response to drug | cellular chemical homeostasis | neurogenesis | glucose homeostasis | negative regulation of protein secretion | positive regulation of cation channel activity | regulation of peptide hormone secretion | generation of neurons | regulation of neuroblast migration | cellular process | negative regulation of gliogenesis | regulation of cell motility | localization | cellular homeostasis | passive transmembrane transporter activity | negative regulation of signaling | metal ion transport | visual learning | female pregnancy | learning | negative regulation of secretion | negative regulation of cell migration | negative regulation of hormone secretion | response to inorganic substance | negative regulation of establishment of protein localization | response to peptide hormone | regulation of cell differentiation | negative regulation of cell motility | negative regulation of wound healing | regulation of angiogenesis | regulation of cellular process | regulation of relaxation of muscle | transmembrane transporter activity | positive regulation of potassium ion transport | positive regulation of tumor necrosis factor production | regulation of peptide secretion | associative learning | regulation of vasculature development | response to stimulus | negative regulation of protein transport | regulation of insulin secretion | positive regulation of potassium ion transmembrane transporter activity | positive regulation of cation transmembrane transport | regulation of cell proliferation | negative regulation of angiogenesis | response to peptide | negative regulation of low-density lipoprotein particle clearance | reproduction | response to molecule of bacterial origin | negative regulation of transport | regulation of protein transport | regulation of wound healing | regulation of peptide transport | response to pH | regulation of potassium ion transmembrane transport | response to nitrogen compound | response to light stimulus | response to external biotic stimulus | system development | reproductive process | negative regulation of secretion by cell | multicellular organism development | cellular glucose homeostasis | learning or memory | regulation of hormone levels | ion transmembrane transport | regulation of hormone secretion | response to lipid | nervous system process | cation transmembrane transporter activity | monovalent inorganic cation transport | positive regulation of ion transmembrane transport | regulation of cell migration | active transmembrane transporter activity | regulation of cellular component movement | cellular potassium ion transport | ion transmembrane transporter activity | potassium ion transport | cognition | negative regulation of peptide hormone secretion | regulation of tumor necrosis factor production | regulation of potassium ion transmembrane transporter activity | negative regulation of response to wounding | response to bacterium | cell communication | positive regulation of transporter activity | regulation of glial cell proliferation | homeostatic process | response to zinc ion | regulation of locomotion | positive regulation of transport | negative regulation of maintenance of permeability of blood-brain barrier | regulation of potassium ion transport | positive regulation of molecular function | cation transmembrane transport | potassium channel activity | positive regulation of potassium ion transmembrane transport | regulation of establishment of protein localization | response to organic substance | visual behavior | metal ion transmembrane transporter activity | response to insulin | anatomical structure development | potassium ion transmembrane transporter activity | positive regulation of uterine smooth muscle relaxation | chemical homeostasis | regulation of secretion | behavior | positive regulation of ion transport | negative regulation of cellular component movement | regulation of protein secretion | inorganic cation transmembrane transport | regulation of ion transmembrane transport | positive regulation of cytokine production | cation channel activity | memory | regulation of response to wounding | regulation of cell communication | regulation of gliogenesis | transmembrane transport | negative regulation of insulin secretion | signaling | inorganic cation transmembrane transporter activity | monovalent inorganic cation transmembrane transporter activity | regulation of transmembrane transporter activity | regulation of ion transmembrane transporter activity | regulation of cytokine production | cation transport | channel activity | response to biotic stimulus | regulation of nervous system development | positive regulation of occluding junction disassembly | regulation of developmental process | regulation of ion transport | developmental process | positive regulation of voltage-gated potassium channel activity | regulation of transport | negative regulation of cell proliferation | negative regulation of vasculature development | regulation of cation channel activity | response to organonitrogen compound | potassium ion transmembrane transport | regulation of low-density lipoprotein particle clearance | ion channel activity | ion transport | positive regulation of relaxation of smooth muscle | cellular response to organic substance | regulation of protein localization | negative regulation of cell development | carbohydrate homeostasis | negative regulation of locomotion | substrate-specific channel activity | negative regulation of cell differentiation | regulation of cellular component organization | response to other organism | signal transduction | regulation of signaling | negative regulation of neurogenesis | multicellular organismal process
GO Cellular Component
exocytic vesicle | integral component of membrane | intracellular membrane-bounded organelle | sarcolemma | synapse | potassium channel complex | organelle membrane | cytoplasmic vesicle | cell | plasma membrane protein complex | intrinsic component of membrane | transport vesicle membrane | inward rectifying potassium channel | cytoplasm | intracellular organelle | presynapse | protein-containing complex | secretory vesicle | endomembrane system | plasma membrane | exocytic vesicle membrane | vesicle | transport vesicle | mitochondrion | integral component of plasma membrane | synaptic vesicle | membrane-bounded organelle | organelle | vesicle membrane | cell periphery | transmembrane transporter complex | cation channel complex | ion channel complex | synaptic vesicle membrane | intracellular vesicle | intracellular | membrane | cytoplasmic vesicle membrane | intrinsic component of plasma membrane
