QuickView for TOP2A;jsessionid=F31FED6080A74ABBA9DB566F5F4EB4EC;jsessionid=C19B8246A02FCDB09F7857F57125DB72 (gene)
- Gene Symbol:
- TOP2A
Bos taurus - Full name:
- topoisomerase (DNA) II alpha 170kDa
- Synonyms:
- N/A
- Genomic Location:
- Chr 19: 41892308-41917595
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
| Protein Names |
|---|
| No proteins found. |
GO Molecular Function
kinase binding | cation binding | protein kinase binding | magnesium ion binding | isomerase activity | enzyme binding | nucleic acid binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | ubiquitin binding | catalytic activity | chromatin binding | ATP binding | protein kinase C binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | DNA binding | purine nucleotide binding | identical protein binding | protein heterodimerization activity | DNA topoisomerase type II (ATP-hydrolyzing) activity | ubiquitin-like protein binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | DNA binding, bending | DNA topoisomerase II activity | protein binding | protein homodimerization activity | protein dimerization activity | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | DNA-dependent ATPase activity | drug binding | histone deacetylase binding | metal ion binding | heterocyclic compound binding | DNA topoisomerase activity | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | protein C-terminus binding | small molecule binding
GO Biological Process
positive regulation of macromolecule biosynthetic process | positive regulation of apoptotic process | regulation of programmed cell death | negative regulation of cellular process | cell differentiation | regulation of organelle organization | positive regulation of viral life cycle | positive regulation of cellular biosynthetic process | cellular process | immune system development | multicellular organismal reproductive process | positive regulation of nitrogen compound metabolic process | gamete generation | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of viral genome replication | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | response to stimulus | female gamete generation | response to stress | hematopoietic progenitor cell differentiation | reproduction | cellular nitrogen compound metabolic process | positive regulation of RNA biosynthetic process | hemopoiesis | embryo development | regulation of nucleic acid-templated transcription | system development | nitrogen compound metabolic process | reproductive process | positive regulation of viral process | multicellular organism development | cellular response to DNA damage stimulus | regulation of gene expression | cellular response to stress | cell cycle | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | cell division | positive regulation of single stranded viral RNA replication via double stranded DNA intermediate | DNA topological change | regulation of cellular metabolic process | regulation of RNA metabolic process | regulation of viral process | negative regulation of DNA duplex unwinding | multicellular organism reproduction | DNA metabolic process | anatomical structure development | nuclear division | metabolic process | regulation of single stranded viral RNA replication via double stranded DNA intermediate | regulation of RNA biosynthetic process | positive regulation of cell death | nucleobase-containing compound metabolic process | organic substance metabolic process | animal organ development | positive regulation of programmed cell death | regulation of chromosome organization | embryonic cleavage | meiotic cell cycle | negative regulation of chromosome organization | regulation of transcription, DNA-templated | DNA ligation | regulation of circadian rhythm | developmental process | organelle organization | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | DNA conformation change | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | chromosome organization | immune system process | cellular metabolic process | regulation of viral genome replication | hematopoietic or lymphoid organ development | regulation of cell death | regulation of viral life cycle | sexual reproduction | regulation of cellular component organization | female meiotic nuclear division | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
chromosome | centriole | intracellular membrane-bounded organelle | microtubule organizing center | DNA topoisomerase complex (ATP-hydrolyzing) | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | nuclear chromosome | ribonucleoprotein complex | microtubule cytoskeleton | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytoskeleton | intracellular | condensed chromosome
