QuickView for TP53;jsessionid=A7FB30FC259DD656C4F43F7145501871;jsessionid=53414598928F5422B231CE9D5FC28036 (gene)
- Gene Symbol:
- tp53
Danio rerio - Full name:
- tumor protein p53
- Synonyms:
- brp53, drp53, fb40d06, p53, wu:fb40d06, zgc:111919
- Genomic Location:
- Chr 5: 13629410-13640862
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Gallus gallus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
AACTTT_UNKNOWN , SOX5_01 , NFKAPPAB65_01 , CREL_01 , NFKAPPAB_01 , MZF1_02 , MYCMAX_02 , ACTAYRNNNCCCR_UNKNOWN , HNF4_01 , AHR_01
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | cation binding | nucleic acid binding | chromatin binding | DNA binding | promoter-specific chromatin binding | ion binding | organic cyclic compound binding | protein binding | DNA-binding transcription factor activity | metal ion binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | protein homooligomerization | response to radiation | cellular response to decreased oxygen levels | positive regulation of macromolecule biosynthetic process | negative regulation of cell division | regulation of cysteine-type endopeptidase activity | epidermis morphogenesis | negative regulation of transposition, RNA-mediated | intracellular signal transduction | positive regulation of apoptotic process | morphogenesis of an epithelium | regulation of programmed cell death | erythrocyte homeostasis | response to X-ray | myeloid cell differentiation | negative regulation of cellular process | epithelial structure maintenance | cell differentiation | male gamete generation | intrinsic apoptotic signaling pathway in response to DNA damage | erythrocyte maturation | tissue homeostasis | regulation of DNA repair | blood vessel morphogenesis | regulation of neuron death | positive regulation of cellular biosynthetic process | cellular process | cell maturation | regulation of transposition | immune system development | multicellular organismal reproductive process | response to hypoxia | regulation of proteolysis | regulation of cell cycle | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | myeloid cell development | tissue development | gamete generation | anatomical structure homeostasis | intrinsic apoptotic signaling pathway | regulation of angiogenesis | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | catabolic process | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | cellular component organization | regulation of cell division | response to UV | regulation of vasculature development | response to stimulus | vasculature development | positive regulation of protein metabolic process | positive regulation of peptidase activity | cellular response to hypoxia | response to stress | cellular nitrogen compound biosynthetic process | multicellular organismal homeostasis | regulation of double-strand break repair | negative regulation of angiogenesis | tube morphogenesis | positive regulation of cysteine-type endopeptidase activity | programmed cell death | reproduction | cardiovascular system development | positive regulation of proteolysis | cellular nitrogen compound metabolic process | positive regulation of RNA biosynthetic process | hemopoiesis | cellular component assembly | cellular biosynthetic process | blood vessel development | myeloid cell homeostasis | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | apoptotic process | response to light stimulus | system development | response to oxygen levels | nitrogen compound metabolic process | reproductive process | DNA damage response, signal transduction by p53 class mediator | regulation of protein stability | multicellular organism development | regulation of peptidase activity | cellular response to DNA damage stimulus | protein complex oligomerization | maintenance of gastrointestinal epithelium | response to methylmercury | regulation of catalytic activity | negative regulation of transposition | DNA damage response, signal transduction resulting in transcription | positive regulation of cell cycle | signal transduction in response to DNA damage | regulation of gene expression | cellular response to stress | cell cycle | positive regulation of cellular metabolic process | digestive system process | cellular response to oxygen levels | regulation of nitrogen compound metabolic process | definitive hemopoiesis | regulation of cysteine-type endopeptidase activity involved in apoptotic process | regulation of transcription by RNA polymerase II | protein homotetramerization | positive regulation of hydrolase activity | homeostasis of number of cells | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | hematopoietic stem cell homeostasis | positive regulation of endopeptidase activity | positive regulation of neuron death | protein tetramerization | epidermis development | positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | erythrocyte development | autophagy | intestinal epithelial structure maintenance | cell communication | regulation of cellular metabolic process | regulation of neuron apoptotic process | regulation of protein metabolic process | apoptotic process involved in development | homeostatic process | regulation of RNA metabolic process | apoptotic signaling pathway | cell aging | positive regulation of molecular function | multicellular organism reproduction | protein-containing complex assembly | DNA-binding transcription factor activity | response to organic substance | tissue morphogenesis | positive regulation of neuron apoptotic process | anatomical structure development | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | metabolic process | regulation of RNA biosynthetic process | developmental maturation | positive regulation of cell death | regulation of response to DNA damage stimulus | nucleobase-containing compound metabolic process | organic substance metabolic process | cell death | animal organ development | gene expression | positive regulation of programmed cell death | intrinsic apoptotic signaling pathway by p53 class mediator | regulation of transposition, RNA-mediated | transcription, DNA-templated | negative regulation of cell cycle | cellular senescence | signaling | regulation of transcription, DNA-templated | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | cell development | anatomical structure morphogenesis | regulation of endopeptidase activity | cellular macromolecule biosynthetic process | regulation of developmental process | developmental process | erythrocyte differentiation | spermatogenesis | digestion | tube development | positive regulation of transcription, DNA-templated | negative regulation of vasculature development | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | apoptotic process involved in morphogenesis | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | regulation of cell death | DNA damage checkpoint | cell cycle checkpoint | signal transduction by p53 class mediator | circulatory system development | aging | sexual reproduction | response to ionizing radiation | apoptotic process involved in blood vessel morphogenesis | signal transduction | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
chromosome | intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | chromatin | membrane-bounded organelle | nucleus | organelle | intracellular
