sequence-specific DNA binding | protein self-association | kinase binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | core promoter binding | histone deacetylase regulator activity | protein phosphatase 2A binding | enhancer binding | cation binding | protein kinase binding | proximal promoter sequence-specific DNA binding | receptor tyrosine kinase binding | enzyme binding | nucleic acid binding | ribonucleotide binding | disordered domain specific binding | mRNA binding | nucleotide binding | signaling receptor binding | carbohydrate derivative binding | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | molecular function regulator | chromatin binding | chaperone binding | protein domain specific binding | ATP binding | protein N-terminus binding | ubiquitin-like protein ligase binding | TFIID-class transcription factor binding | anion binding | adenyl nucleotide binding | enhancer sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | p53 binding | DNA binding | MDM2/MDM4 family protein binding | sequence-specific double-stranded DNA binding | purine nucleotide binding | promoter-specific chromatin binding | identical protein binding | protein heterodimerization activity | ion binding | organic cyclic compound binding | protein tyrosine kinase binding | copper ion binding | transcription regulatory region sequence-specific DNA binding | purine ribonucleoside triphosphate binding | protein binding | histone acetyltransferase binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | protein phosphatase binding | transcription factor binding | ubiquitin protein ligase binding | RNA polymerase II transcription factor binding | protein dimerization activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | RNA polymerase II distal enhancer sequence-specific DNA binding | transition metal ion binding | core promoter sequence-specific DNA binding | purine ribonucleotide binding | enzyme regulator activity | adenyl ribonucleotide binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding involved in preinitiation complex assembly | drug binding | transcription factor activity, core RNA polymerase binding | protease binding | phosphatase binding | mRNA 3'-UTR binding | transcription cofactor binding | histone deacetylase binding | metal ion binding | basal RNA polymerase II transcription machinery binding | heterocyclic compound binding | protein C-terminus binding | small molecule binding | RNA binding
RNA metabolic process | transcription by RNA polymerase II | response to extracellular stimulus | positive regulation of transcription from RNA polymerase II promoter in response to hypoxia | regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter | brain development | protein homooligomerization | double-strand break repair | DNA-templated transcription, initiation | response to radiation | regulation of hydrogen peroxide-induced cell death | regulation of cell cycle process | cellular response to glucose starvation | cellular response to decreased oxygen levels | positive regulation of macromolecule biosynthetic process | positive regulation of locomotion | response to nutrient levels | positive regulation of cell aging | response to endoplasmic reticulum stress | release of cytochrome c from mitochondria | DNA strand renaturation | response to cytokine | regulation of cellular response to oxidative stress | positive regulation of cellular component organization | regulation of response to oxidative stress | regulation of neurogenesis | intracellular signal transduction | positive regulation of apoptotic process | regulation of cell development | protein stabilization | regulation of localization | regulation of cell cycle G1/S phase transition | regulation of carbohydrate metabolic process | regulation of programmed cell death | regulation of mitochondrial membrane permeability involved in apoptotic process | positive regulation of peptidyl-tyrosine phosphorylation | T cell lineage commitment | regulation of cell aging | response to X-ray | necroptotic process | mitochondrial DNA metabolic process | establishment of localization | regulation of autophagy | regulation of immune system process | negative regulation of neuroblast proliferation | regulation of transforming growth factor beta receptor signaling pathway | neuron death | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of developmental process | negative regulation of RNA biosynthetic process | regulation of cardiac muscle cell apoptotic process | cell differentiation | positive regulation of intrinsic apoptotic signaling pathway | defense response | nervous system development | intrinsic apoptotic signaling pathway in response to DNA damage | cellular response to extracellular stimulus | negative regulation of mitochondrion organization | response to drug | multicellular organism growth | cellular chemical homeostasis | histone deacetylase regulator activity | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | regulation of G1/S transition of mitotic cell cycle | neurogenesis | positive regulation of phosphate metabolic process | regulation of protein oligomerization | regulation of DNA replication | regulation of organelle organization | positive regulation of cellular component movement | negative regulation of glucose catabolic process to lactate via pyruvate | generation of neurons | membrane organization | B cell differentiation | response to antibiotic | intracellular transport | regulation of neuroblast proliferation | negative regulation of DNA metabolic process | negative regulation of proteolysis | pattern specification process | regulation of neuron death | positive regulation of cellular biosynthetic process | regulation of transcription initiation from RNA polymerase II promoter | cellular process | negative regulation of DNA biosynthetic process | lymphocyte differentiation | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress | regulation of cell motility | localization | cellular homeostasis | regulation of glycolytic process | chromatin organization | mitotic DNA integrity checkpoint | protein transport | heart morphogenesis | negative regulation of macroautophagy | negative regulation of signaling | developmental growth | negative regulation of G1/S transition of mitotic cell cycle | positive regulation of reactive oxygen species metabolic process | programmed necrotic cell death | immune system development | negative regulation of nucleic acid-templated transcription | macromolecule localization | regulation of histone modification | negative regulation of apoptotic process | response to hypoxia | positive regulation of release of cytochrome c from mitochondria | cellular response to starvation | regulation of proteolysis | positive regulation of T cell apoptotic process | regulation of cell cycle | response to growth factor | positive regulation of nitrogen compound metabolic process | positive regulation of muscle cell apoptotic process | establishment of localization in cell | negative regulation of cellular metabolic process | tissue development | regulation of cell differentiation | interspecies interaction between organisms | DNA geometric change | intrinsic apoptotic signaling pathway | regulation of lymphocyte apoptotic process | regulation of cellular process | leukocyte activation | regulation of apoptotic process | regulation of metabolic process | interferon-gamma-mediated signaling pathway | catabolic process | regulation of protein complex assembly | protein import into nucleus | organic cyclic compound metabolic process | positive regulation of cellular protein metabolic process | RNA biosynthetic process | epithelium development | cellular response to organonitrogen compound | cellular aromatic compound metabolic process | signal transduction involved in mitotic DNA damage checkpoint | cellular component organization | negative regulation of nucleotide metabolic process | response to transforming growth factor beta | T cell activation | cellular response to interferon-gamma | response to UV | head development | negative regulation of DNA replication | stress-induced premature senescence | response to stimulus | regulation of mitotic cell cycle phase transition | regulation of peptidyl-tyrosine phosphorylation | metencephalon development | positive regulation of immune system process | positive regulation of protein metabolic process | mononuclear cell proliferation | response to salt stress | cellular response to light stimulus | cellular response to hypoxia | response to stress | intracellular protein transport | leukocyte activation involved in immune response | cellular nitrogen compound biosynthetic process | regulation of response to drug | regulation of cell proliferation | response to peptide | protein localization to nucleus | regulation of cell cycle phase transition | circadian rhythm | response to starvation | response to actinomycin D | positive regulation of protein deacetylation | positive regulation of thymocyte apoptotic process | programmed cell death | protein-DNA complex assembly | cellular localization | rhythmic process | cellular nitrogen compound metabolic process | response to ischemia | regulation of macroautophagy | apoptotic mitochondrial changes | transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | hemopoiesis | cellular component assembly | mRNA metabolic process | cellular biosynthetic process | embryo development | mitochondrion organization | negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway | cellular response to UV-C | positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus | negative regulation of autophagy of mitochondrion | molecular function regulator | positive regulation of membrane permeability | positive regulation of mitochondrion organization | DNA repair | anterior/posterior pattern specification | regulation of nucleic acid-templated transcription | negative regulation of cellular response to transforming growth factor beta stimulus | leukocyte differentiation | regulation of cellular response to stress | response to nitrogen compound | apoptotic process | cellular response to actinomycin D | response to light stimulus | negative regulation of mitophagy | system development | cellular response to nutrient levels | response to oxygen levels | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of mitotic cell cycle phase transition | positive regulation of organelle organization | DNA damage response, signal transduction by p53 class mediator | negative regulation of growth | regulation of protein stability | negative regulation of phosphate metabolic process | cellular response to antibiotic | mitotic DNA damage checkpoint | multicellular organism development | negative regulation of catalytic activity | negative regulation of ATP metabolic process | positive regulation of RNA polymerase II transcriptional preinitiation complex assembly | protein import into nucleus, translocation | cellular response to DNA damage stimulus | protein complex oligomerization | regulation of catalytic activity | cerebellum development | cellular response to oxidative stress | ER-nucleus signaling pathway | regulation of phosphorylation | regulation of intrinsic apoptotic signaling pathway | ncRNA transcription | positive regulation of chromosome organization | DNA damage response, signal transduction resulting in transcription | positive regulation of cell cycle | signal transduction in response to DNA damage | regulation of gene expression | T cell proliferation involved in immune response | oligodendrocyte apoptotic process | regulation of mitochondrial membrane permeability | rhythmic behavior | organic substance transport | cellular response to stress | cellular response to peptide | cell cycle | regulation of stem cell proliferation | regulation of signal transduction by p53 class mediator | regulation of cell cycle arrest | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of telomerase activity | cellular ion homeostasis | cellular response to radiation | animal organ morphogenesis | regulation of pri-miRNA transcription by RNA polymerase II | negative regulation of smooth muscle cell proliferation | mitochondrial transport | cellular response to oxygen levels | glial cell apoptotic process | regulation of nitrogen compound metabolic process | regulation of cell migration | enzyme linked receptor protein signaling pathway | neuron apoptotic process | peptide transport | cytokine-mediated signaling pathway | negative regulation of cellular response to growth factor stimulus | positive regulation of intracellular signal transduction | positive regulation of protein complex assembly | regulation of cellular component movement | regulation of transcription by RNA polymerase II | protein homotetramerization | cellular response to gamma radiation | response to oxidative stress | rRNA transcription | protein localization to organelle | import into nucleus | positive regulation of cell migration | cellular response to cytokine stimulus | B cell activation | cell proliferation | leukocyte proliferation | biosynthetic process | response to osmotic stress | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | positive regulation of transcription from RNA polymerase II promoter in response to stress | hindbrain development | oxidative stress-induced premature senescence | T cell activation involved in immune response | positive regulation of pri-miRNA transcription by RNA polymerase II | regulation of RNA polymerase II transcriptional preinitiation complex assembly | cardiac septum morphogenesis | cellular protein-containing complex assembly | positive regulation of neuron death | protein tetramerization | positive regulation of leukocyte apoptotic process | rRNA metabolic process | regulation of apoptotic signaling pathway | DNA-templated transcriptional preinitiation complex assembly | signal transduction involved in cell cycle checkpoint | response to gamma radiation | RNA polymerase II transcriptional preinitiation complex assembly | cation homeostasis | regulation of leukocyte migration | cellular response to UV | autophagy | negative regulation of autophagy | protein import | regulation of mitochondrion organization | regulation of cellular response to drug | mitotic G1 DNA damage checkpoint | regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter | mitochondrial membrane organization | regulation of muscle cell apoptotic process | chordate embryonic development | positive regulation of histone deacetylation | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | mitochondrial genome maintenance | transmembrane receptor protein serine/threonine kinase signaling pathway | regulation of protein deacetylation | regulation of neuron apoptotic process | regulation of intracellular pH | regulation of T cell apoptotic process | cell activation involved in immune response | regulation of protein metabolic process | positive regulation of signal transduction | heart development | negative regulation of stem cell proliferation | homeostatic process | mRNA transcription | regulation of protein phosphorylation | intrinsic apoptotic signaling pathway in response to hypoxia | regulation of locomotion | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | viral process | negative regulation of cell growth | regulation of cellular response to growth factor stimulus | apoptotic signaling pathway | cell aging | embryonic morphogenesis | ER overload response | mitochondrial DNA repair | regulation of mitotic cell cycle | regulation of autophagy of mitochondrion | lymphocyte activation | cellular response to transforming growth factor beta stimulus | positive regulation of cell cycle arrest | positive regulation of execution phase of apoptosis | T cell differentiation | protein-containing complex assembly | negative regulation of carbohydrate metabolic process | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | regulation of fibroblast proliferation | DNA-binding transcription factor activity | regionalization | negative regulation of transforming growth factor beta receptor signaling pathway | positive regulation of protein modification process | regulation of growth | response to organic substance | T cell differentiation in thymus | G1 DNA damage checkpoint | cell cycle arrest | regulation of pH | DNA metabolic process | replicative senescence | regulation of response to reactive oxygen species | regulation of intracellular signal transduction | chromatin assembly or disassembly | positive regulation of neuron apoptotic process | establishment of protein localization to organelle | anatomical structure development | mitotic cell cycle | cell surface receptor signaling pathway | entrainment of circadian clock | regulation of glucose metabolic process | regulation of neural precursor cell proliferation | intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator | metabolic process | cell fate commitment | nucleotide-excision repair | regulation of DNA-templated transcription in response to stress | positive regulation of DNA-templated transcription, initiation | regulation of thymocyte apoptotic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | embryonic organ development | negative regulation of mitotic cell cycle | cellular protein localization | regulation of tissue remodeling | amide transport | intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress | chemical homeostasis | behavior | positive regulation of cell death | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | immune response | nucleobase-containing compound metabolic process | cellular response to reactive oxygen species | positive regulation of mitochondrial membrane permeability | positive regulation of cellular component biogenesis | organic substance metabolic process | nuclear transport | cell death | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | positive regulation of histone modification | response to reactive oxygen species | negative regulation of cellular protein metabolic process | T cell proliferation | gene expression | positive regulation of leukocyte migration | positive regulation of programmed cell death | signal transduction involved in mitotic cell cycle checkpoint | ion homeostasis | cellular response to ionizing radiation | regulation of ATP metabolic process | regulation of phosphate metabolic process | DNA packaging | regulation of chromosome organization | intrinsic apoptotic signaling pathway by p53 class mediator | establishment of protein localization | transcription initiation from RNA polymerase II promoter | transcription, DNA-templated | response to interferon-gamma | regulation of cellular pH | cell activation | positive regulation of lymphocyte apoptotic process | chromatin assembly | transforming growth factor beta receptor signaling pathway | negative regulation of fermentation | anatomical structure formation involved in morphogenesis | positive regulation of cardiac muscle cell apoptotic process | negative regulation of cell cycle | negative regulation of protein metabolic process | B cell lineage commitment | lymphocyte proliferation | multicellular organism aging | regulation of cell communication | negative regulation of cell cycle G1/S phase transition | regulation of membrane permeability | negative regulation of molecular function | cellular senescence | negative regulation of signal transduction | signaling | somite development | mitotic cell cycle arrest | regulation of transcription, DNA-templated | response to UV-C | cellular monovalent inorganic cation homeostasis | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator | determination of adult lifespan | protein localization | negative regulation of fibroblast proliferation | positive regulation of phosphorylation | enzyme regulator activity | regulation of transcription from RNA polymerase II promoter in response to stress | anatomical structure morphogenesis | cellular macromolecule localization | cellular macromolecule biosynthetic process | regulation of DNA-templated transcription, initiation | signal transduction involved in DNA damage checkpoint | response to biotic stimulus | nucleocytoplasmic transport | regulation of circadian rhythm | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding involved in preinitiation complex assembly | regulation of nervous system development | regulation of developmental process | transcription factor activity, core RNA polymerase binding | regulation of transcription from RNA polymerase II promoter in response to hypoxia | regulation of intrinsic apoptotic signaling pathway by p53 class mediator | segmentation | developmental process | organelle organization | regulation of DNA biosynthetic process | positive regulation of cell cycle process | regulation of cell growth | cardiac septum development | mitotic G1/S transition checkpoint | negative regulation of transcription by RNA polymerase II | positive regulation of transcription, DNA-templated | regulation of reactive oxygen species metabolic process | positive regulation of protein oligomerization | necrotic cell death | negative regulation of cell proliferation | negative regulation of neural precursor cell proliferation | innate immune response | ncRNA metabolic process | circadian behavior | positive regulation of nucleic acid-templated transcription | entrainment of circadian clock by photoperiod | DNA conformation change | response to organonitrogen compound | positive regulation of transcription by RNA polymerase II | photoperiodism | cardiac chamber development | heterocycle metabolic process | regulation of fibroblast apoptotic process | regulation of histone deacetylation | somitogenesis | signal transduction involved in mitotic G1 DNA damage checkpoint | central nervous system development | regulation of generation of precursor metabolites and energy | in utero embryonic development | positive regulation of metabolic process | chromosome organization | regulation of execution phase of apoptosis | gastrulation | immune system process | mitotic cell cycle checkpoint | cellular metabolic process | hematopoietic or lymphoid organ development | negative regulation of cell cycle process | cellular response to organic substance | regulation of cell death | regulation of smooth muscle cell proliferation | positive regulation of cell motility | DNA damage checkpoint | cell cycle checkpoint | signal transduction by p53 class mediator | negative regulation of cell death | negative regulation of cell development | circulatory system development | aging | negative regulation of telomerase activity | negative regulation of cell differentiation | regulation of cellular component organization | response to ionizing radiation | positive regulation of transcription initiation from RNA polymerase II promoter | positive regulation of apoptotic signaling pathway | negative regulation of reactive oxygen species metabolic process | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | cellular response to growth factor stimulus | macromolecule metabolic process | negative regulation of neurogenesis | regulation of cellular senescence | multicellular organismal process | regulation of chromatin organization | regulation of phosphorus metabolic process
nuclear transcription factor complex | mitochondrial matrix | site of DNA damage | chromosome | intracellular membrane-bounded organelle | catalytic complex | RNA polymerase II transcription factor complex | cell | nuclear lumen | transcription factor complex | replication fork | nucleolus | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear body | protein-containing complex | PML body | endomembrane system | nucleoplasm | chromatin | nuclear chromosome | transferase complex | mitochondrion | site of double-strand break | membrane-bounded organelle | nucleus | organelle | nuclear DNA-directed RNA polymerase complex | transcription factor TFIID complex | RNA polymerase complex | membrane-enclosed lumen | nuclear matrix | nuclear chromatin | cytosol | intracellular | RNA polymerase II, holoenzyme | nuclear periphery