QuickView for TPM1;jsessionid=CE00107156928F7C065B4124D92AC625;jsessionid=6FCE893011B89FA2E0D4943238D2F9BC (gene)

Gene Symbol:

Tpm1 Rattus norvegicus

Full name:

tropomyosin 1

Synonyms:

Alpha-tm, Tma2, Tmsa, tropomyosin alpha-1 chain, hepatoma alpha tropomyosin, smooth muscle alpha-tropomyosin, striated muscle alpha-tropomyosin, tropomyosin 1, alpha, tropomyosin 3 alpha, tropomyosin-alpha

Genomic Location:

Chr 8: 71331304-71358063

Description:

This gene is a member of the tropomyosin family and encodes a protein that heterodimerizes with a beta subunit, binding actin in both muscle and nonmuscle cells. In both smooth and striated muscle cells, it plays a role in calcium dependent-regulation of muscle contraction. In nonmuscle cells, it stabilizes cytoskeleton actin filaments. Alternate t...

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This gene is a member of the tropomyosin family and encodes a protein that heterodimerizes with a beta subunit, binding actin in both muscle and nonmuscle cells. In both smooth and striated muscle cells, it plays a role in calcium dependent-regulation of muscle contraction. In nonmuscle cells, it stabilizes cytoskeleton actin filaments. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

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Orthologs:

Homo sapiens ,  Mus musculus ,  D. melanogaster ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

YY1_01 ,  EVI1_04 ,  SRF_01 ,  CEBP_01 ,  TATA_01 ,  OLF1_01 ,  AML1_01 ,  GATA1_05 ,  PAX4_01 ,  E2F1_Q4 ,  NKX3A_01 ,  HNF4ALPHA_Q6 ,  ZF5_01 ,  AML1_Q6 ,  PIT1_Q6 ,  SRF_Q4 ,  GR_Q6_01 ,  T3R_Q6 ,  TGGTGCT_MIR29A_MIR29B_MIR29C ,  GTGGGTGK_UNKNOWN ,  GTGCCAT_MIR183 ,  TAGCTTT_MIR9 ,  GTGCCAA_MIR96 ,  WTTGKCTG_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  TGGAAA_NFAT_Q4_01 ,  CCCNNGGGAR_OLF1_01 ,  WGGAATGY_TEF1_Q6

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miRNA binding sites
(Source: miRecords):

rno-miR-21 Targeted Genes ,  rno-miR-29c Targeted Genes ,  rno-miR-338 Targeted Genes

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