QuickView for TRKB;jsessionid=BEE68A6FE0CD85BEF242000C9EF7FEEF;jsessionid=4F7219ABDAD16E2426D065AF261AA28C (gene)

GO Molecular Function

kinase binding | neurotrophin binding | transmembrane receptor protein tyrosine kinase activity | protein kinase binding | transmembrane signaling receptor activity | receptor tyrosine kinase binding | enzyme binding | ribonucleotide binding | nucleotide binding | signaling receptor binding | carbohydrate derivative binding | protein serine/threonine kinase activity | growth factor binding | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | brain-derived neurotrophic factor binding | signaling receptor activity | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | protein tyrosine kinase binding | purine ribonucleoside triphosphate binding | protein tyrosine kinase activity | protein binding | protein homodimerization activity | transmembrane receptor protein serine/threonine kinase activity | brain-derived neurotrophic factor-activated receptor activity | protein dimerization activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | neurotrophin receptor activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | small molecule binding

GO Biological Process

regulation of ERK1 and ERK2 cascade | brain development | response to radiation | long-term memory | response to cytokine | positive regulation of cellular component organization | cell motility | regulation of cell morphogenesis | regulation of neurogenesis | regulation of cellular localization | intracellular signal transduction | regulation of synapse assembly | regulation of cell development | regulation of localization | regulation of programmed cell death | peptidyl-amino acid modification | transmembrane receptor protein tyrosine kinase activity | eye development | establishment of localization | negative regulation of neuron death | neuron migration | negative regulation of cellular process | positive regulation of developmental process | cellular response to tumor necrosis factor | cell differentiation | defense response | nervous system development | positive regulation of axonogenesis | neurogenesis | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | generation of neurons | blood vessel morphogenesis | regulation of neuron death | cellular process | secretion | peripheral nervous system development | localization | positive regulation of synaptic transmission | negative regulation of signaling | positive regulation of peptidyl-serine phosphorylation | neuron development | central nervous system neuron differentiation | negative regulation of anoikis | dicarboxylic acid transport | anion transport | learning | negative regulation of apoptotic process | response to growth factor | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | retinal rod cell development | regulation of cell differentiation | regulation of protein kinase B signaling | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | gliogenesis | response to nerve growth factor | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | cellular component organization | head development | response to stimulus | vasculature development | acid secretion | positive regulation of protein metabolic process | positive regulation of phosphatidylinositol 3-kinase signaling | response to stress | regulation of intracellular steroid hormone receptor signaling pathway | regulation of cell proliferation | tube morphogenesis | circadian rhythm | protein serine/threonine kinase activity | secretion by cell | cardiovascular system development | rhythmic process | regulation of anoikis | protein modification process | regulation of synapse structure or activity | modulation of chemical synaptic transmission | positive regulation of synaptic transmission, glutamatergic | macromolecule modification | cell-cell signaling | eye photoreceptor cell differentiation | blood vessel development | regulation of neurotransmitter levels | locomotion | response to nitrogen compound | negative regulation of neuron apoptotic process | central nervous system neuron development | response to light stimulus | system development | nitrogen compound metabolic process | regulation of signal transduction | positive regulation of neuron projection development | multicellular organism development | cell migration | regulation of synaptic transmission, glutamatergic | regulation of MAPK cascade | phosphorus metabolic process | response to amino acid | learning or memory | regulation of axonogenesis | regulation of catalytic activity | cellular response to nerve growth factor stimulus | regulation of phosphorylation | mechanoreceptor differentiation | telencephalon development | regulation of neuron differentiation | regulation of gene expression | organic substance transport | nervous system process | synaptic signaling | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | neuromuscular junction development | animal organ morphogenesis | regulation of synapse organization | protein autophosphorylation | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | positive regulation of cell projection organization | positive regulation of intracellular signal transduction | organic acid transport | synapse organization | positive regulation of cell differentiation | second-messenger-mediated signaling | cognition | cellular response to cytokine stimulus | regulation of cellular protein metabolic process | neurotrophin signaling pathway | glial cell differentiation | organic anion transport | phosphorylation | regulation of GTPase activity | cellular response to amino acid stimulus | protein phosphorylation | phosphate-containing compound metabolic process | sensory organ development | cell communication | regulation of cellular metabolic process | eye morphogenesis | transmembrane receptor protein serine/threonine kinase signaling pathway | regulation of neuron apoptotic process | inflammatory response | regulation of protein metabolic process | positive regulation of signal transduction | vasculogenesis | positive regulation of cell proliferation | regulation of protein phosphorylation | brain-derived neurotrophic factor receptor signaling pathway | positive regulation of synapse assembly | eye photoreceptor cell development | cerebral cortex development | amino acid transport | protein tyrosine kinase activity | calcium-mediated signaling | neuron differentiation | regulation of cell morphogenesis involved in differentiation | protein metabolic process | transmembrane receptor protein serine/threonine kinase activity | positive regulation of protein modification process | response to organic substance | retina development in camera-type eye | response to mechanical stimulus | brain-derived neurotrophic factor-activated receptor activity | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | positive regulation of neurogenesis | metabolic process | positive regulation of cell development | trans-synaptic signaling by neuropeptide, modulating synaptic transmission | positive regulation of glucocorticoid receptor signaling pathway | negative regulation of programmed cell death | peripheral nervous system neuron development | oligodendrocyte differentiation | regulation of secretion | behavior | protein kinase activity | positive regulation of cellular component biogenesis | organic substance metabolic process | animal organ development | forebrain development | pallium development | positive regulation of ERK1 and ERK2 cascade | cellular response to brain-derived neurotrophic factor stimulus | regulation of phosphate metabolic process | neurotrophin receptor activity | positive regulation of MAPK cascade | camera-type eye development | regulation of peptidyl-serine phosphorylation | memory | regulation of dendrite development | regulation of cell communication | negative regulation of signal transduction | signaling | feeding behavior | positive regulation of intracellular steroid hormone receptor signaling pathway | cell development | positive regulation of phosphorylation | cellular protein metabolic process | carboxylic acid transport | anatomical structure morphogenesis | glutamate secretion | regulation of nervous system development | regulation of developmental process | kinase activity | developmental process | cellular protein modification process | calcium-mediated signaling using intracellular calcium source | tube development | regulation of transport | response to organonitrogen compound | photoreceptor cell development | central nervous system development | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | regulation of synaptic plasticity | positive regulation of neuron differentiation | ion transport | regulation of cell projection organization | cellular metabolic process | long-term synaptic potentiation | response to tumor necrosis factor | photoreceptor cell differentiation | cellular response to organic substance | regulation of cell death | peripheral nervous system neuron differentiation | positive regulation of cell morphogenesis involved in differentiation | negative regulation of cell death | circulatory system development | aging | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of phosphatidylinositol 3-kinase signaling | regulation of signaling | positive regulation of gene expression | response to auditory stimulus | regulation of neurotransmitter secretion | cellular response to growth factor stimulus | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

dendritic spine | integral component of membrane | dendrite | intracellular membrane-bounded organelle | early endosome membrane | synapse | neuron projection | somatodendritic compartment | organelle membrane | cytoplasmic vesicle | cell body | cell | neuronal cell body | distal axon | intrinsic component of membrane | synaptic membrane | terminal bouton | cytoplasm | intracellular organelle | receptor complex | endoplasmic reticulum | dendritic tree | presynapse | endosome membrane | Golgi apparatus | protein-containing complex | cell projection | postsynaptic membrane | endomembrane system | neuron spine | postsynapse | plasma membrane | perikaryon | vesicle | perinuclear region of cytoplasm | postsynaptic density | asymmetric synapse | site of polarized growth | integral component of plasma membrane | Golgi membrane | endosome | membrane-bounded organelle | organelle | postsynaptic specialization | axon terminus | presynaptic active zone | cell periphery | excitatory synapse | axon | early endosome | growth cone | neuron projection terminus | rough endoplasmic reticulum | cytosol | intracellular vesicle | cell surface | intracellular | membrane | intrinsic component of plasma membrane

PATHWAYS

PID_SHP2_PATHWAY | PID_AJDISS_2PATHWAY | PID_TRKR_PATHWAY | REACTOME_SIGNALLING_BY_NGF | REACTOME_NGF_SIGNALLING_VIA_TRKA_FROM_THE_PLASMA_MEMBRANE

PROTEIN FAMILY

Leucine-rich repeat N-terminal domain | Cysteine-rich flanking region, C-terminal | Protein kinase domain | Serine-threonine/tyrosine-protein kinase, catalytic domain | Leucine-rich repeat | Tyrosine-protein kinase, receptor class II, conserved site | Immunoglobulin subtype 2 | Immunoglobulin subtype | Immunoglobulin-like domain | Tyrosine-protein kinase, active site | Protein kinase-like domain superfamily | Immunoglobulin I-set | Immunoglobulin-like fold | Protein kinase, ATP binding site | Tyrosine-protein kinase, neurotrophic receptor, type 2 | Tyrosine-protein kinase, catalytic domain | Tyrosine-protein kinase, neurotrophic receptor | Tyrosine-protein kinase receptor NTRK, C2-Ig-like domain | Leucine-rich repeat domain superfamily | Immunoglobulin-like domain superfamily