QuickView for UCP2;jsessionid=734A182AEDFCD733FD8073A614039A90;jsessionid=3BE277E1467B1DF766CD272738935EED (gene)
- Gene Symbol:
- Ucp2
Rattus norvegicus - Full name:
- uncoupling protein 2
- Synonyms:
- mitochondrial uncoupling protein 2, UCP 2, Uncoupling protein 2, mitochondrial, solute carrier family 25 member 8, uncoupling protein 2 (mitochondrial, proton carrier)
- Genomic Location:
- Chr 1: 157922179-157928518
- Description:
-
catalyzes a proton leak across the inner mitochondrial membrane to uncouple oxidative phosphorylation; may reduce the concentration of reactive ozygen species in mitochondria
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Bos taurus , Canis lupus familiaris , Pan troglodytes , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
transmembrane transporter activity | transporter activity | oxidative phosphorylation uncoupler activity
GO Biological Process
response to extracellular stimulus | response to nutrient levels | cellular response to glucose stimulus | regulation of cellular localization | negative regulation of peptide secretion | regulation of localization | regulation of programmed cell death | establishment of localization | response to hormone | negative regulation of cellular process | cellular response to extracellular stimulus | cellular chemical homeostasis | glucose homeostasis | negative regulation of protein secretion | regulation of peptide hormone secretion | adaptive thermogenesis | cellular process | proton transmembrane transport | localization | cellular homeostasis | regulation of mitochondrial membrane potential | negative regulation of signaling | female pregnancy | negative regulation of apoptotic process | negative regulation of secretion | response to hypoxia | cellular response to starvation | negative regulation of hormone secretion | response to inorganic substance | negative regulation of establishment of protein localization | response to peptide hormone | regeneration | regulation of cellular process | regulation of apoptotic process | hepaticobiliary system development | transmembrane transporter activity | cellular response to organonitrogen compound | regulation of peptide secretion | response to stimulus | negative regulation of protein transport | regulation of insulin secretion | response to cold | response to stress | response to peptide | response to glucose | response to starvation | reproduction | response to temperature stimulus | negative regulation of transport | regulation of protein transport | regulation of peptide transport | regulation of membrane potential | response to nitrogen compound | cellular response to hormone stimulus | system development | cellular response to nutrient levels | response to oxygen levels | reproductive process | negative regulation of secretion by cell | multicellular organism development | cellular glucose homeostasis | cellular response to peptide hormone stimulus | response to fatty acid | cellular response to insulin stimulus | regulation of insulin secretion involved in cellular response to glucose stimulus | regulation of hormone levels | ion transmembrane transport | regulation of hormone secretion | cellular response to amino acid starvation | cellular response to stress | response to lipid | cellular response to peptide | monovalent inorganic cation transport | liver development | mitochondrial transport | response to superoxide | response to oxidative stress | response to oxygen radical | negative regulation of peptide hormone secretion | cell communication | liver regeneration | homeostatic process | response to monosaccharide | negative regulation of insulin secretion involved in cellular response to glucose stimulus | oxidative phosphorylation uncoupler activity | cation transmembrane transport | regulation of establishment of protein localization | response to organic substance | gland development | response to insulin | anatomical structure development | metabolic process | negative regulation of programmed cell death | cellular response to carbohydrate stimulus | chemical homeostasis | regulation of secretion | positive regulation of cell death | mitochondrial transmembrane transport | animal organ development | response to reactive oxygen species | regulation of protein secretion | inorganic cation transmembrane transport | regulation of cell communication | transmembrane transport | negative regulation of insulin secretion | cation transport | developmental process | regulation of transport | response to organonitrogen compound | response to amino acid starvation | ion transport | cellular response to organic substance | regulation of protein localization | regulation of cell death | response to carbohydrate | negative regulation of cell death | aging | carbohydrate homeostasis | regulation of signaling | animal organ regeneration | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | intracellular
