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QuickView for UGT1A1;jsessionid=137D157AE4E16BCE090BE8A20B64C9F1;jsessionid=DE6F7CFD3B6DD3E000D159E3FCB8EA7D;jsessionid=59264BDA072D05BC21519A770475FDC9;jsessionid=74AE302F8CAAB90280FD3E1A69F365BF (gene)


Gene Symbol:
Ugt1a1 Rattus norvegicus Rattus norvegicus
Full name:
UDP glucuronosyltransferase family 1 member A1
Synonyms:
UDPGT 1-1, Udpgt, Ugt1, UDP-glucuronosyltransferase 1-1, B1, UDP glucuronosyltransferase 1 family, polypeptide A1, UDP glycosyltransferase 1 family, polypeptide A1, UDP-glucuronosyltransferase 1 family member 1, UDP-glucuronosyltransferase 1A1, UGT1*1, UGT1-01, UGT1.1
Genomic Location:
Chr 9: 87091241-87098362
Description:
catalyzes the glucuronidation of bilirubin; plays a role in bilirubin conjugation and excretion
Orthologs:
Homo sapiens Mus musculus Macaca mulatta Gallus gallus Pan troglodytes Danio rerio Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:


Transcripts Names
NM_012683
Protein Names
Q64635
Q64550
Q5DT04



GO Molecular Function

isoprenoid binding | retinoid binding | carboxylic acid binding | enzyme binding | lipid binding | enzyme inhibitor activity | UDP-glycosyltransferase activity | molecular function regulator | catalytic activity | anion binding | identical protein binding | transferase activity, transferring glycosyl groups | protein heterodimerization activity | ion binding | organic cyclic compound binding | protein binding | protein homodimerization activity | protein dimerization activity | transferase activity, transferring hexosyl groups | transferase activity | enzyme regulator activity | retinoic acid binding | steroid binding | glucuronosyltransferase activity | organic acid binding | small molecule binding

GO Biological Process

response to extracellular stimulus | response to nutrient levels | response to lipopolysaccharide | negative regulation of cellular glucuronidation | regulation of carbohydrate metabolic process | response to hormone | negative regulation of cellular process | defense response | response to drug | xenobiotic catabolic process | benzene-containing compound metabolic process | response to antibiotic | cellular process | organic substance catabolic process | response to estradiol | negative regulation of cellular metabolic process | porphyrin-containing compound metabolic process | regeneration | regulation of cellular process | cellular response to lipid | regulation of metabolic process | xenobiotic metabolic process | catabolic process | hepaticobiliary system development | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | response to stimulus | enzyme inhibitor activity | monocarboxylic acid metabolic process | cellular response to xenobiotic stimulus | response to stress | flavone metabolic process | response to starvation | response to alcohol | response to molecule of bacterial origin | cellular nitrogen compound metabolic process | cellular response to toxic substance | cellular response to ethanol | cellular response to organic cyclic compound | negative regulation of metabolic process | cofactor metabolic process | molecular function regulator | response to ethanol | cellular response to hormone stimulus | response to external biotic stimulus | system development | nitrogen compound metabolic process | cellular response to antibiotic | multicellular organism development | negative regulation of catalytic activity | antibiotic metabolic process | regulation of catalytic activity | response to lipid | liver development | monosaccharide metabolic process | small molecule metabolic process | response to corticosteroid | response to nutrient | glucuronate metabolic process | acute-phase response | cellular response to glucocorticoid stimulus | flavonoid metabolic process | carbohydrate metabolic process | response to toxic substance | response to xenobiotic stimulus | cellular response to corticosteroid stimulus | cellular response to drug | response to bacterium | regulation of cellular metabolic process | inflammatory response | aromatic compound catabolic process | drug metabolic process | carboxylic acid metabolic process | negative regulation of carbohydrate metabolic process | response to organic substance | gland development | biphenyl metabolic process | anatomical structure development | metabolic process | biphenyl catabolic process | bilirubin conjugation | organic substance metabolic process | pigment metabolic process | animal organ development | cellular glucuronidation | cellular response to steroid hormone stimulus | organonitrogen compound catabolic process | cellular response to estradiol stimulus | negative regulation of molecular function | response to organic cyclic compound | organic acid metabolic process | enzyme regulator activity | response to biotic stimulus | regulation of cellular ketone metabolic process | developmental process | flavonoid glucuronidation | heterocycle metabolic process | acute inflammatory response | cellular metabolic process | cellular response to organic substance | response to steroid hormone | xenobiotic glucuronidation | response to other organism | animal organ regeneration | response to glucocorticoid | multicellular organismal process

GO Cellular Component

endoplasmic reticulum chaperone complex | integral component of membrane | intracellular membrane-bounded organelle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | endomembrane system | endoplasmic reticulum membrane | plasma membrane | cytochrome complex | integral component of plasma membrane | membrane-bounded organelle | organelle | cell periphery | intracellular | membrane | intrinsic component of plasma membrane