QuickView for UGT2B7;jsessionid=C985E4988F65868046707D1029727E52;jsessionid=16822D9CC3C7133EF9A6550A62682B95;jsessionid=BEE215AD17CDBE677991B16763DEF732;jsessionid=C2F2BBA8588D4CB2B8FDFFFA62C76315 (gene)

Gene Symbol:

UGT2B7 Homo sapiens

Full name:

UDP glucuronosyltransferase family 2 member B7

Synonyms:

UDPGT 2B7, UDPGT 2B9, UDPGT2B7, UDPGTH2, UDPGTh-2, UGT2B9, UDP-glucuronosyltransferase 2B7, 3,4-catechol estrogen specific, 3,4-catechol estrogen-specific UDPGT, UDP glucuronosyltransferase 2 family, polypeptide B7, UDP-glucuronosyltransferase 2B9, UDP-glucuronyltransferase, family 2, beta-7

Genomic Location:

Chr 4: 69996814-70013293

Description:

The protein encoded by this gene belongs to the UDP-glycosyltransferase (UGT) family. UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This protein is localized in the microsome membrane, and has unique specificity for 3,4-catechol estrogens and estriol, suggesting that...

View Full Description

The protein encoded by this gene belongs to the UDP-glycosyltransferase (UGT) family. UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This protein is localized in the microsome membrane, and has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Alternative splicing results in multiple transcript variants.

View Less

Orthologs:

Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes

External Links:

Entrez Gene

Cytogenetic Map:

4q13.2

search → result