QuickView for Vav2;jsessionid=A4A1B343780B36FCC07BF946B11082EA;jsessionid=5B78D652B681D0D574387042D9160ACB (gene)

Gene Symbol:

Vav2 Mus musculus

Full name:

vav 2 oncogene

Synonyms:

2810040F13Rik, AI847175, Vav-2, guanine nucleotide exchange factor VAV2

Genomic Location:

Chr 2: 27119155-27282347

Description:

This gene encodes a member of the Vav family of Rho guanine nucleotide exchange factors. Vav family proteins are involved in the development and activation of lymphocytes, and the encoded protein may also be involved in angiogenesis. Disruption of this gene in mice is associated with heart, artery, and kidney defects, as well as tachycardia and hyp...

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This gene encodes a member of the Vav family of Rho guanine nucleotide exchange factors. Vav family proteins are involved in the development and activation of lymphocytes, and the encoded protein may also be involved in angiogenesis. Disruption of this gene in mice is associated with heart, artery, and kidney defects, as well as tachycardia and hypertension. Alternative splicing results in multiple transcript variants.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Danio rerio ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

MAF_Q6 ,  TGCTGCT_MIR15A_MIR16_MIR15B_MIR195_MIR424_MIR497 ,  GCTCTTG_MIR335 ,  TTGCCAA_MIR182 ,  CTTTGT_LEF1_Q2

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-125 ,  Predicted Gene Targets for miR-15 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-335 ,  Predicted Gene Targets for miR-182 ,  Predicted Gene Targets for miR-410

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