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QuickView for YDL100C;jsessionid=173C30357403D04B74AAEA94DC2D080B;jsessionid=7AF66EE79FD83162841140D5B5D60D51;jsessionid=9F7940AAAE2F1AB30A80145D3B0311A4;jsessionid=2834D262230A3C9734EB5E1989A27E7C (gene)


Gene Symbol:
ASNA1 Homo sapiens Homo sapiens
Full name:
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
Synonyms:
ARSA-I, ARSA1, ASNA-I, GET3, TRC40, ATPase ASNA1, golgi to ER traffic 3 homolog, transmembrane domain recognition complex 40 kDa ATPase subunit
Genomic Location:
Chr 19: 12709306-12720137
Description:
This gene represents the human homolog of the bacterial arsA gene, encoding the arsenite-stimulated ATPase component of the arsenite transporter responsible for resistance to arsenicals. This protein is also a central component of a transmembrane domain (TMD) recognition complex (TRC) that is involved in the post-translational delivery of tail-anch...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Danio rerio Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 19
19p13.13


Transcripts Names
NM_004317
Protein Names
Q92849
Q53FC6
O43681
A8K740
A6NHP8



GO Molecular Function

anion transmembrane transporter activity | cation binding | ribonucleotide binding | transmembrane transporter activity | nucleotide binding | hydrolase activity | carbohydrate derivative binding | ATPase activity | pyrophosphatase activity | inorganic anion transmembrane transporter activity | catalytic activity | ATP binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | purine nucleotide binding | transporter activity | ion transmembrane transporter activity | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | arsenite transmembrane transporter activity | metal ion binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding

GO Biological Process

response to endoplasmic reticulum stress | establishment of localization | protein targeting to ER | anion transmembrane transporter activity | membrane organization | intracellular transport | posttranslational protein targeting to endoplasmic reticulum membrane | cellular process | localization | protein transport | protein localization to endoplasmic reticulum | anion transport | macromolecule localization | endoplasmic reticulum unfolded protein response | endomembrane system organization | establishment of localization in cell | regulation of cellular process | transmembrane transporter activity | cellular response to unfolded protein | response to topologically incorrect protein | cellular component organization | cellular response to topologically incorrect protein | response to stimulus | response to stress | intracellular protein transport | inorganic anion transport | cellular localization | protein insertion into ER membrane | inorganic anion transmembrane transporter activity | ion transmembrane transport | protein localization to membrane | organic substance transport | cellular response to stress | peptide transport | ion transmembrane transporter activity | protein localization to organelle | protein insertion into membrane | cell communication | establishment of protein localization to membrane | response to organic substance | tail-anchored membrane protein insertion into ER membrane | anion transmembrane transport | IRE1-mediated unfolded protein response | establishment of protein localization to organelle | establishment of protein localization to endoplasmic reticulum | cellular protein localization | amide transport | establishment of protein localization | transmembrane transport | signaling | protein localization | response to unfolded protein | cellular macromolecule localization | protein targeting to membrane | organelle organization | arsenite transport | arsenite transmembrane transporter activity | protein targeting | ion transport | cellular response to organic substance | endoplasmic reticulum organization | signal transduction

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | nucleolus | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | protein-containing complex | endomembrane system | endoplasmic reticulum membrane | vesicle | extracellular exosome | GET complex | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | membrane-enclosed lumen | intracellular | membrane