Correlation Engine 2.0
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QuickView for YDL142C;jsessionid=B0D8A131B333D5F452CE2C656B00943D;jsessionid=A290500D254D430250FD3AB1C60BBC36;jsessionid=10ED555007950742FC618A28D7DE3934 (gene)


Gene Symbol:
CRLS1 Homo sapiens Homo sapiens
Full name:
cardiolipin synthase 1
Synonyms:
C20orf155, CLS, CLS1, GCD10, dJ967N21.6, cardiolipin synthase (CMP-forming)
Genomic Location:
Chr 20: 5934879-5966039
Description:
This gene encodes a member of the CDP-alcohol phosphatidyltransferase class-I family of proteins. The encoded enzyme catalyzes the synthesis of cardiolipin, a phospholipid component of mitochondrial membranes that is critical for mitochondrial function.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Bos taurus Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 20
20p12.3





GO Molecular Function

phosphotransferase activity, for other substituted phosphate groups | transferase activity, transferring acyl groups other than amino-acyl groups | 2-acylglycerol-3-phosphate O-acyltransferase activity | cardiolipin synthase activity | catalytic activity | lysophosphatidic acid acyltransferase activity | transferase activity, transferring acyl groups | acylglycerol O-acyltransferase activity | CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity | transferase activity, transferring phosphorus-containing groups | transferase activity | lysophospholipid acyltransferase activity | 1-acylglycerol-3-phosphate O-acyltransferase activity | O-acyltransferase activity

GO Biological Process

phosphatidylglycerol acyl-chain remodeling | phosphatidylglycerol metabolic process | response to hormone | phosphatidylglycerol biosynthetic process | response to drug | phospholipid metabolic process | response to organophosphorus | cellular process | cardiolipin biosynthetic process | cellular lipid metabolic process | response to stimulus | cellular biosynthetic process | response to nitrogen compound | phosphorus metabolic process | response to amino acid | lipid metabolic process | response to lipid | organophosphate metabolic process | phospholipid biosynthetic process | cardiolipin metabolic process | biosynthetic process | lipid biosynthetic process | phosphate-containing compound metabolic process | glycerolipid metabolic process | response to organic substance | response to L-phenylalanine derivative | glycerophospholipid biosynthetic process | response to phosphatidylethanolamine | metabolic process | organic substance metabolic process | response to organic cyclic compound | glycerophospholipid metabolic process | response to thyroid hormone | response to organonitrogen compound | response to thyroxine | cellular metabolic process

GO Cellular Component

integral component of membrane | organelle inner membrane | intracellular membrane-bounded organelle | mitochondrial inner membrane | organelle membrane | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | mitochondrial envelope | mitochondrial membrane | intracellular | membrane