QuickView for YDL143W;jsessionid=AF9A6F4065C670FDF1AB5408FD20ADBE;jsessionid=91A7B07E4FBC9ADE18D402AED915E385;jsessionid=9FE4C78D66C4B32B6D01F989153F658E;jsessionid=5005A9092D0CB4D0936EDC4B6556712E (gene)

Gene Symbol:

CCT4 Homo sapiens

Full name:

chaperonin containing TCP1 subunit 4

Synonyms:

CCT-DELTA, Cctd, SRB, T-complex protein 1 subunit delta, TCP-1-delta, chaperonin containing TCP1, subunit 4 (delta), chaperonin containing t-complex polypeptide 1, delta subunit, stimulator of TAR RNA-binding

Genomic Location:

Chr 2: 61948766-61969295

Description:

The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediat...

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The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TTCNRGNNNNTTC_HSF_Q6 ,  RGAANNTTC_HSF1_01 ,  TTCYRGAA_UNKNOWN ,  HSF2_01

Cytogenetic Map:

2p15

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