QuickView for ZBTB7A;jsessionid=513CD80E86B5CC4EBAB8B13BF2C61192;jsessionid=B498F709ED03CB0630C8B719835E79E2 (gene)
- Gene Symbol:
- Zbtb7a
Rattus norvegicus - Full name:
- zinc finger and BTB domain containing 7a
- Synonyms:
- Lrf, OCZF, Zbtb7, zinc finger and BTB domain-containing protein 7A, leukemia/lymphoma-related factor, osteoclast-derived zinc finger protein
- Genomic Location:
- Chr 7: 10047586-10060463
- Description:
-
acts as a transcriptional repressor; may play a role in osteoclastogenesis
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Danio rerio , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
E4BP4_01 , TAXCREB_01 , CREBP1_Q2 , ISRE_01 , OLF1_01 , ETS2_B , GATA1_05 , CCTNTMAGA_UNKNOWN , VDR_Q3 , GATA6_01
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-99 , Predicted Gene Targets for miR-125 , Predicted Gene Targets for miR-148 , Predicted Gene Targets for miR-20 , Predicted Gene Targets for miR-30 , Predicted Gene Targets for miR-539 , Predicted Gene Targets for miR-542-3p , Predicted Gene Targets for miR-93 , Predicted Gene Targets for miR-376 , Predicted Gene Targets for miR-137
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | cation binding | proximal promoter sequence-specific DNA binding | enzyme binding | nucleic acid binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | ion binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | histone acetyltransferase binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | DNA-binding transcription factor activity | RNA polymerase II regulatory region sequence-specific DNA binding | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | metal ion binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | regulation of immune system process | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | negative regulation of RNA biosynthetic process | cell differentiation | cellular process | negative regulation of nucleic acid-templated transcription | regulation of myeloid cell differentiation | negative regulation of cellular metabolic process | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | negative regulation of metabolic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | multicellular organism development | regulation of gene expression | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | regulation of RNA metabolic process | DNA-binding transcription factor activity | regulation of hemopoiesis | anatomical structure development | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | transcription, DNA-templated | regulation of osteoclast differentiation | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | regulation of developmental process | developmental process | negative regulation of transcription by RNA polymerase II | heterocycle metabolic process | cellular metabolic process | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | intracellular organelle | membrane-bounded organelle | nucleus | organelle | intracellular
