QuickView for ZNF597;jsessionid=A7230B06A434D2CC66F33B0BD42BE921;jsessionid=42E558CFC991E72564A981CD1FEA3A5A;jsessionid=29AE1BAB9551DC5683956C2625CB00CE (gene)
- Gene Symbol:
- ZNF597
Homo sapiens - Full name:
- zinc finger protein 597
- Synonyms:
- HIT-4, zinc finger protein 597
- Genomic Location:
- Chr 16: 3426111-3433491
- Description:
-
This gene encodes a protein with multiple zinc finger domains. Loss of the related gene in rodents results in defects in neural development and embryonic lethality in mutant homozygotes. This gene is adjacent to a differentially methylated region (DMR) and is imprinted and maternally expressed.
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
16p13.3
GO Molecular Function
sequence-specific DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | cation binding | nucleic acid binding | DNA binding | ion binding | organic cyclic compound binding | DNA-binding transcription factor activity | metal ion binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | positive regulation of macromolecule biosynthetic process | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | negative regulation of RNA biosynthetic process | positive regulation of cellular biosynthetic process | cellular process | negative regulation of nucleic acid-templated transcription | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | regulation of nucleic acid-templated transcription | nitrogen compound metabolic process | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | aromatic compound biosynthetic process | regulation of cellular metabolic process | regulation of RNA metabolic process | DNA-binding transcription factor activity | metabolic process | regulation of RNA biosynthetic process | negative regulation of transcription, DNA-templated | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | gene expression | transcription, DNA-templated | regulation of transcription, DNA-templated | cellular macromolecule biosynthetic process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | positive regulation of gene expression | macromolecule metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | cell | nuclear lumen | intracellular organelle | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | intracellular
