QuickView for bean;jsessionid=0C82C0179E285F5BB041C4ACA47AB053;jsessionid=B94C7407F91D546A3EFF251DF03855CD;jsessionid=3C8AD26E47D14364A7BEB0D4253306E7;jsessionid=CC2DA480CCE7F3CDB51D7A05E7EEADFF (gene)

Gene Symbol:

BEAN1 Homo sapiens

Full name:

brain expressed associated with NEDD4 1

Synonyms:

BEAN, SCA31, protein BEAN1, brain-expressed protein associating with Nedd4 homolog

Genomic Location:

Chr 16: 65018120-65074249

Description:

The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of ...

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The protein encoded by this gene is one of several proteins that interact with NEDD4, a member of a family of ubiquitin-protein ligases. These proteins have PY motifs in common that bind to the WW domains of NEDD4. NEDD4 is developmentally regulated, and is highly expressed in embryonic tissues. Mutations in this gene (i.e., intronic insertions of >100 copies of pentanucleotide repeats including a (TGGAA)n sequence) are associated with spinocerebellar ataxia type 31. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus

External Links:

Entrez Gene

Cytogenetic Map:

16q21

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