QuickView for clusterin;jsessionid=7144D780FDBBB81E3BDB56A42EFEB815;jsessionid=0A166F9DBCA224787B1E17564A98AE81 (gene)
- Gene Symbol:
- CLU
Canis lupus familiaris - Full name:
- clusterin
- Synonyms:
- GP80
- Genomic Location:
- Chr 25: 32971386-32988141
- Orthologs:
- Homo sapiens , Mus musculus , Rattus norvegicus , Macaca mulatta , Bos taurus , Danio rerio , Gallus gallus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
GATA1_01 , CEBP_Q2 , STAT_01 , LMO2COM_02 , STAT5B_01 , STAT_Q6 , GATA_Q6 , SYATTGTG_UNKNOWN , TCCATTKW_UNKNOWN , TTANWNANTGGM_UNKNOWN
GO Molecular Function
enzyme binding | hydrolase activity | ATPase activity | pyrophosphatase activity | catalytic activity | chaperone binding | ubiquitin-like protein ligase binding | nucleoside-triphosphatase activity | protein binding | misfolded protein binding | ubiquitin protein ligase binding | hydrolase activity, acting on acid anhydrides | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO Biological Process
intracellular signal transduction | positive regulation of apoptotic process | protein stabilization | positive regulation of DNA-binding transcription factor activity | regulation of programmed cell death | negative regulation of protein homooligomerization | negative regulation of cellular process | positive regulation of proteasomal ubiquitin-dependent protein catabolic process | response to misfolded protein | positive regulation of intrinsic apoptotic signaling pathway | positive regulation of protein catabolic process | regulation of protein oligomerization | cellular process | chaperone-mediated protein folding | negative regulation of signaling | negative regulation of apoptotic process | regulation of proteolysis | positive regulation of nitrogen compound metabolic process | intrinsic apoptotic signaling pathway | negative regulation of apoptotic signaling pathway | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | regulation of protein complex assembly | positive regulation of cellular protein metabolic process | response to topologically incorrect protein | positive regulation of cellular protein catabolic process | response to stimulus | positive regulation of protein metabolic process | regulation of cellular protein catabolic process | response to stress | programmed cell death | positive regulation of proteolysis involved in cellular protein catabolic process | positive regulation of proteolysis | negative regulation of protein oligomerization | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage | regulation of nucleic acid-templated transcription | regulation of cellular response to stress | apoptotic process | regulation of signal transduction | regulation of protein stability | regulation of intrinsic apoptotic signaling pathway | regulation of gene expression | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | regulation of cellular protein metabolic process | positive regulation of proteasomal protein catabolic process | regulation of apoptotic signaling pathway | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | regulation of RNA metabolic process | apoptotic signaling pathway | positive regulation of molecular function | regulation of proteasomal ubiquitin-dependent protein catabolic process | regulation of protein homooligomerization | response to organic substance | regulation of DNA-binding transcription factor activity | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | positive regulation of ubiquitin-dependent protein catabolic process | regulation of protein catabolic process | regulation of RNA biosynthetic process | negative regulation of programmed cell death | regulation of proteasomal protein catabolic process | positive regulation of cell death | regulation of response to DNA damage stimulus | negative regulation of protein complex assembly | negative regulation of intrinsic apoptotic signaling pathway | protein folding | regulation of intrinsic apoptotic signaling pathway in response to DNA damage | cell death | positive regulation of NF-kappaB transcription factor activity | positive regulation of programmed cell death | regulation of cell communication | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | positive regulation of metabolic process | regulation of cell death | negative regulation of cell death | regulation of ubiquitin-dependent protein catabolic process | regulation of cellular component organization | positive regulation of apoptotic signaling pathway | positive regulation of signaling | signal transduction | regulation of signaling
GO Cellular Component
secretory granule | chromaffin granule | intracellular membrane-bounded organelle | extracellular matrix | organelle membrane | cytoplasmic vesicle | cell | spherical high-density lipoprotein particle | cytoplasm | collagen-containing extracellular matrix | intracellular organelle | lipoprotein particle | endoplasmic reticulum | Golgi apparatus | protein-containing complex | secretory vesicle | endomembrane system | protein-lipid complex | vesicle | endoplasmic reticulum lumen | perinuclear region of cytoplasm | mitochondrion | extracellular region | membrane-bounded organelle | nucleus | organelle | mitochondrial envelope | high-density lipoprotein particle | extracellular space | membrane-enclosed lumen | plasma lipoprotein particle | mitochondrial membrane | cytosol | intracellular vesicle | intracellular | membrane
