QuickView for colorless;jsessionid=C75D28D3D95964345224CB5FCF9DF625;jsessionid=6138D5E0585FFC14877B1FD87B37803F (gene)
- Gene Symbol:
- Sox10
Rattus norvegicus - Full name:
- SRY box 10
- Synonyms:
- transcription factor SOX-10, SRY (sex determining region Y)-box 10, SRY-box containing gene 10
- Genomic Location:
- Chr 7: 117138694-117149939
- Description:
-
transcription factor asociated with the sex determining factor SRY; may be important for glial cell development and cell specificity
- Orthologs:
- Homo sapiens , Mus musculus , Macaca mulatta , Danio rerio , Bos taurus , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
NFKAPPAB65_01 , CREL_01 , NFKAPPAB_01 , CP2_01 , GATA3_01 , ACCTGTTG_UNKNOWN , TAXCREB_01 , CEBPB_02 , USF_02 , MYCMAX_02
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
sequence-specific DNA binding | transcription factor activity, transcription factor binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | enhancer binding | transcription factor activity, RNA polymerase II transcription factor binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | chromatin binding | enhancer sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | promoter-specific chromatin binding | identical protein binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | transcriptional activator activity, RNA polymerase II transcription factor binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | transcription factor binding | RNA polymerase II regulatory region sequence-specific DNA binding | RNA polymerase II distal enhancer sequence-specific DNA binding | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | heterocyclic compound binding
GO Biological Process
RNA metabolic process | transcription by RNA polymerase II | transcription factor activity, transcription factor binding | positive regulation of macromolecule biosynthetic process | cell motility | regulation of neurogenesis | regulation of cell development | cellular response to progesterone stimulus | morphogenesis of an epithelium | regulation of programmed cell death | negative regulation of glial cell proliferation | response to hormone | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of developmental process | negative regulation of RNA biosynthetic process | cell differentiation | nervous system development | response to drug | neurogenesis | generation of neurons | mesenchyme development | regulation of neuroblast proliferation | positive regulation of neurological system process | positive regulation of cellular biosynthetic process | cellular process | negative regulation of gliogenesis | peripheral nervous system development | localization | axon ensheathment | cell maturation | negative regulation of signaling | developmental growth | response to progesterone | negative regulation of nucleic acid-templated transcription | negative regulation of apoptotic process | digestive tract morphogenesis | positive regulation of nitrogen compound metabolic process | transcription factor activity, RNA polymerase II transcription factor binding | regulation of canonical Wnt signaling pathway | central nervous system myelination | negative regulation of cellular metabolic process | tissue development | regulation of neurological system process | regulation of cell differentiation | autonomic nervous system development | regulation of cellular process | regulation of apoptotic process | cellular response to lipid | regulation of metabolic process | gliogenesis | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | positive regulation of myelination | response to stimulus | lacrimal gland development | mesenchymal cell development | oligodendrocyte development | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | positive regulation of neuroblast proliferation | tube morphogenesis | ensheathment of neurons | pigment cell differentiation | axon ensheathment in central nervous system | cellular nitrogen compound metabolic process | positive regulation of gliogenesis | cellular response to organic cyclic compound | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | embryo development | regulation of nucleic acid-templated transcription | locomotion | cellular response to hormone stimulus | system development | nitrogen compound metabolic process | regulation of signal transduction | myelination | multicellular organism development | cell migration | negative regulation of Schwann cell proliferation | regulation of gene expression | response to ketone | response to lipid | regulation of stem cell proliferation | positive regulation of cellular metabolic process | developmental pigmentation | enteric nervous system development | regulation of myelination | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | pigmentation | positive regulation of cell differentiation | stem cell differentiation | biosynthetic process | aromatic compound biosynthetic process | glial cell differentiation | digestive tract development | transcription elongation from RNA polymerase II promoter | cellular response to drug | neural crest cell migration | chordate embryonic development | regulation of cellular metabolic process | regulation of glial cell proliferation | positive regulation of cell proliferation | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | transcriptional activator activity, RNA polymerase II transcription factor binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | response to organic substance | gland development | tissue morphogenesis | digestive system development | anatomical structure development | positive regulation of neurogenesis | regulation of neural precursor cell proliferation | metabolic process | positive regulation of cell development | mesenchymal cell differentiation | regulation of RNA biosynthetic process | developmental maturation | negative regulation of transcription, DNA-templated | negative regulation of programmed cell death | oligodendrocyte differentiation | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | gene expression | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding | regulation of Wnt signaling pathway | cellular response to steroid hormone stimulus | transcription, DNA-templated | stem cell development | morphogenesis of a branching epithelium | regulation of cell communication | regulation of gliogenesis | negative regulation of signal transduction | regulation of transcription, DNA-templated | glial cell development | response to organic cyclic compound | cell development | morphogenesis of a branching structure | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | positive regulation of stem cell proliferation | regulation of nervous system development | regulation of developmental process | melanocyte differentiation | positive regulation of neural precursor cell proliferation | developmental process | negative regulation of canonical Wnt signaling pathway | tube development | positive regulation of transcription, DNA-templated | negative regulation of cell proliferation | positive regulation of nucleic acid-templated transcription | neural crest cell differentiation | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | central nervous system development | in utero embryonic development | positive regulation of metabolic process | negative regulation of Wnt signaling pathway | cellular metabolic process | ameboidal-type cell migration | cellular response to organic substance | exocrine system development | regulation of cell death | response to steroid hormone | negative regulation of cell death | negative regulation of cell development | neural crest cell development | negative regulation of cell differentiation | regulation of signaling | positive regulation of gene expression | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process | DNA-templated transcription, elongation
GO Cellular Component
chromosome | intracellular membrane-bounded organelle | extrinsic component of organelle membrane | extrinsic component of membrane | organelle membrane | cell | organelle outer membrane | nuclear lumen | cytoplasm | intracellular organelle | nucleoplasm | chromatin | mitochondrion | membrane-bounded organelle | nucleus | organelle | mitochondrial outer membrane | mitochondrial envelope | membrane-enclosed lumen | outer membrane | extrinsic component of mitochondrial outer membrane | mitochondrial membrane | intracellular | membrane
