QuickView for cyp2b6;jsessionid=1650FDE97AF17F3716292CFF1DB5646D;jsessionid=A385AD9BA2402797434184B5FFBFB0C7 (gene)
- Gene Symbol:
- Cyp2b2
Rattus norvegicus - Full name:
- cytochrome P450, family 2, subfamily b, polypeptide 2
- Synonyms:
- CYPIIB2, Cype, cytochrome P450 2B2, cytochrome P-450b type e, cytochrome P-450e-M, cytochrome P450 PB4, cytochrome P450, subfamily IIB (phenobarbital-inducible)(b, e), cytochrome P450E
- Genomic Location:
- Chr 1: 81345408-81359416
- Description:
-
phenobarbital-inducible member of the p450 xenobiotic-inducible superfamily that metabolizes nicotine and some drugs and activates carcinogens
- Orthologs:
- Homo sapiens , Mus musculus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cofactor binding | cation binding | steroid hydroxylase activity | iron ion binding | catalytic activity | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | ion binding | organic cyclic compound binding | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | arachidonic acid monooxygenase activity | tetrapyrrole binding | transition metal ion binding | heme binding | metal ion binding | heterocyclic compound binding | oxidoreductase activity | aromatase activity | arachidonic acid epoxygenase activity
GO Biological Process
response to metal ion | response to drug | cellular process | response to inorganic substance | xenobiotic metabolic process | catabolic process | steroid hydroxylase activity | response to stimulus | cellular response to xenobiotic stimulus | drug catabolic process | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | monooxygenase activity | small molecule metabolic process | exogenous drug catabolic process | response to xenobiotic stimulus | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen | arachidonic acid monooxygenase activity | drug metabolic process | response to organic substance | metabolic process | oxidation-reduction process | organic substance metabolic process | nicotine metabolic process | response to organic cyclic compound | organic acid metabolic process | developmental process | response to calcium ion | cellular metabolic process | oxidoreductase activity | aromatase activity | aging | arachidonic acid epoxygenase activity
GO Cellular Component
intracellular membrane-bounded organelle | organelle membrane | cell | cytoplasm | intracellular organelle | endoplasmic reticulum | nuclear outer membrane-endoplasmic reticulum membrane network | endomembrane system | endoplasmic reticulum membrane | membrane-bounded organelle | organelle | intracellular | membrane
