QuickView for frdA;jsessionid=2E2EDE944854D68EAC8414EC89E6AD75;jsessionid=A1D703F39CCFC8525077F96764E7715E (gene)
- Gene Symbol:
- Fxn
Mus musculus - Full name:
- frataxin
- Synonyms:
- FA, FARR, Frda, X25, frataxin, mitochondrial, Friedreich ataxia
- Genomic Location:
- Chr 19: 24335943-24355076
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Bos taurus , Danio rerio , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
GO Molecular Function
cofactor binding | ferric iron binding | cation binding | enzyme binding | ferrous iron binding | iron chaperone activity | iron ion binding | oxidoreductase activity, oxidizing metal ions | catalytic activity | iron-sulfur cluster binding | ferroxidase activity | ion binding | protein binding | 2 iron, 2 sulfur cluster binding | metallochaperone activity | transition metal ion binding | metal ion binding | oxidoreductase activity
GO Biological Process
purine ribonucleotide metabolic process | positive regulation of cellular component organization | regulation of cell morphogenesis | regulation of neurogenesis | positive regulation of lyase activity | proteolysis | regulation of cell development | sulfur compound metabolic process | regulation of programmed cell death | establishment of localization | negative regulation of cellular process | positive regulation of developmental process | protein processing | response to metal ion | cell differentiation | negative regulation of organ growth | nervous system development | negative regulation of mitochondrion organization | response to drug | generation of precursor metabolites and energy | cellular chemical homeostasis | positive regulation of axonogenesis | neurogenesis | regulation of organelle organization | aerobic respiration | generation of neurons | response to antibiotic | cellular process | localization | cellular homeostasis | nucleotide metabolic process | negative regulation of signaling | walking behavior | negative regulation of developmental growth | cellular respiration | ribose phosphate metabolic process | negative regulation of apoptotic process | positive regulation of oxidoreductase activity | nucleoside triphosphate metabolic process | positive regulation of catalytic activity | regulation of multicellular organism growth | negative regulation of release of cytochrome c from mitochondria | ribonucleotide metabolic process | regulation of neuron projection development | response to inorganic substance | regulation of cell differentiation | heme metabolic process | porphyrin-containing compound metabolic process | negative regulation of apoptotic signaling pathway | response to hydrogen peroxide | regulation of cellular process | positive regulation of cell growth | regulation of apoptotic process | regulation of metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | response to stimulus | purine nucleotide metabolic process | iron-sulfur cluster assembly | oxidoreductase activity, oxidizing metal ions | positive regulation of succinate dehydrogenase activity | response to stress | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | tetrapyrrole biosynthetic process | cellular nitrogen compound metabolic process | cellular response to toxic substance | regulation of cellular component size | cofactor metabolic process | cellular component assembly | regulation of axon extension | protein modification process | cellular biosynthetic process | embryo development | mitochondrion organization | response to iron ion | macromolecule modification | metal ion homeostasis | system development | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of growth | positive regulation of neuron projection development | cellular response to antibiotic | multicellular organism development | phosphorus metabolic process | neuromuscular process controlling posture | regulation of axonogenesis | regulation of catalytic activity | cellular response to oxidative stress | positive regulation of aconitate hydratase activity | proprioception | regulation of neuron differentiation | cellular response to stress | nervous system process | adult walking behavior | organophosphate metabolic process | cellular ion homeostasis | cofactor biosynthetic process | adult locomotory behavior | pigment biosynthetic process | small molecule metabolic process | positive regulation of cell projection organization | response to oxidative stress | heme biosynthetic process | positive regulation of cell differentiation | nucleobase-containing small molecule metabolic process | biosynthetic process | locomotory behavior | aromatic compound biosynthetic process | phosphorylation | ferroxidase activity | negative regulation of multicellular organism growth | protein maturation | response to toxic substance | regulation of apoptotic signaling pathway | cation homeostasis | phosphate-containing compound metabolic process | cellular response to drug | regulation of mitochondrion organization | cellular cation homeostasis | homeostatic process | positive regulation of cell proliferation | embryo development ending in birth or egg hatching | iron ion homeostasis | drug metabolic process | positive regulation of molecular function | positive regulation of axon extension | regulation of cell morphogenesis involved in differentiation | protein metabolic process | regulation of growth | anatomical structure development | positive regulation of neurogenesis | metabolic process | positive regulation of cell development | oxidation-reduction process | negative regulation of programmed cell death | cellular response to hydrogen peroxide | chemical homeostasis | behavior | oxidative phosphorylation | nucleobase-containing compound metabolic process | cellular response to reactive oxygen species | organic substance metabolic process | pigment metabolic process | response to reactive oxygen species | gene expression | ion homeostasis | cellular iron ion homeostasis | iron incorporation into metallo-sulfur cluster | protein autoprocessing | regulation of ferrochelatase activity | adult behavior | sensory perception | regulation of cell communication | negative regulation of signal transduction | positive regulation of developmental growth | positive regulation of growth | regulation of oxidoreductase activity | neuromuscular process | regulation of developmental growth | cellular protein metabolic process | regulation of cell size | regulation of organ growth | regulation of nervous system development | regulation of developmental process | energy derivation by oxidation of organic compounds | developmental process | organelle organization | regulation of cell growth | cellular protein modification process | carbohydrate derivative metabolic process | cellular metal ion homeostasis | heterocycle metabolic process | positive regulation of metabolic process | positive regulation of neuron differentiation | ion transport | regulation of cell projection organization | transition metal ion homeostasis | cellular metabolic process | ATP metabolic process | regulation of cell death | oxidoreductase activity | positive regulation of cell morphogenesis involved in differentiation | negative regulation of cell death | porphyrin-containing compound biosynthetic process | regulation of cellular component organization | regulation of signaling | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | protein-containing complex | mitochondrion | L-cysteine desulfurase complex | membrane-bounded organelle | organelle | cytosol | intracellular
