QuickView for inhA;jsessionid=55876650DAE3E68898AFF9F3C8B845E7;jsessionid=AF68CFA0FE9F21ED59DEA8BA507C3A7D (gene)

Gene Symbol:

Inha Mus musculus

Full name:

inhibin alpha

Synonyms:

AW555078, inhibin alpha chain

Genomic Location:

Chr 1: 75503652-75506929

Description:

This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the ...

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This gene encodes a member of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate multiple peptide products, including the alpha subunit of the inhibin A and B protein complexes. These complexes negatively regulate follicle stimulating hormone secretion from the pituitary gland. Inhibins have also been implicated in regulating numerous cellular processes including cell proliferation, apoptosis, immune response and hormone secretion. Mice in which this gene has been ablated exhibit sex cord-stromal tumors and symptoms that mimic the human cancer cachexia syndrome.

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Orthologs:

Homo sapiens ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Canis lupus familiaris ,  Danio rerio ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E47_01 ,  P300_01 ,  COMP1_01 ,  GATA1_01 ,  GATA3_01 ,  GATA1_02 ,  GATA1_04 ,  AP4_Q6 ,  MYOD_Q6 ,  GATA_C ,  LMO2COM_01 ,  LMO2COM_02 ,  PAX3_B ,  VDR_Q3 ,  CTGCAGY_UNKNOWN ,  RP58_01 ,  TFIII_Q6 ,  MYOGENIN_Q6 ,  CACCCBINDINGFACTOR_Q6 ,  GATA_Q6 ,  NRF2_Q4 ,  CAGCTG_AP4_Q5 ,  CAGGTG_E12_Q6 ,  RYTTCCTG_ETS2_B ,  GATAAGR_GATA_C ,  CTTTGA_LEF1_Q2 ,  GGGAGGRR_MAZ_Q6 ,  GCANCTGNY_MYOD_Q6 ,  GATTGGY_NFY_Q6_01 ,  GGGCGGR_SP1_Q6

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