Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for kisspeptin;jsessionid=A3362E0ADB4CD72C27CC8185E2E7EAD2;jsessionid=4D0E17E8F3C6D9BE058FDF0B930EBEA9 (gene)


Gene Symbol:
KISS1 Homo sapiens Homo sapiens
Full name:
KiSS-1 metastasis suppressor
Synonyms:
HH13, KiSS-1, metastasis-suppressor KiSS-1, kisspeptin-1, malignant melanoma metastasis-suppressor, metastin, prepro-kisspeptin
Genomic Location:
Chr 1: 202426092-202432242
Description:
This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, per...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 1
1q32.1


Transcripts Names
NM_002256
Protein Names
Q15726
A8K6N0
Q9HBP1



GO Molecular Function

kisspeptin receptor binding | signaling receptor binding | neuropeptide receptor binding | protein binding | G-protein coupled receptor binding

GO Biological Process

regulation of localization | negative regulation of cellular process | cellular chemical homeostasis | positive regulation of phosphate metabolic process | regulation of peptide hormone secretion | cellular process | cellular homeostasis | positive regulation of synaptic transmission | regulation of growth hormone secretion | multicellular organismal reproductive process | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | regulation of cytosolic calcium ion concentration | positive regulation of cellular protein metabolic process | cellular component organization | calcium ion homeostasis | regulation of peptide secretion | response to stimulus | positive regulation of protein metabolic process | regulation of cell proliferation | ovulation cycle | reproduction | rhythmic process | positive regulation of hormone secretion | G-protein coupled receptor signaling pathway | regulation of peptide transport | modulation of chemical synaptic transmission | metal ion homeostasis | positive regulation of peptide secretion | reproductive process | regulation of signal transduction | generation of ovulation cycle rhythm | regulation of MAPK cascade | regulation of phosphorylation | regulation of hormone levels | regulation of hormone secretion | positive regulation of secretion | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | cellular ion homeostasis | positive regulation of luteinizing hormone secretion | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | positive regulation of intracellular signal transduction | regulation of cellular protein metabolic process | cation homeostasis | ovulation cycle process | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | regulation of endocrine process | regulation of protein metabolic process | positive regulation of signal transduction | cellular calcium ion homeostasis | homeostatic process | regulation of protein phosphorylation | positive regulation of transport | positive regulation of peptide hormone secretion | multicellular organism reproduction | positive regulation of protein modification process | regulation of intracellular signal transduction | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway | chemical homeostasis | regulation of secretion | ion homeostasis | regulation of phosphate metabolic process | cytoskeleton organization | phospholipase C-activating G-protein coupled receptor signaling pathway | positive regulation of MAPK cascade | regulation of cell communication | signaling | positive regulation of phosphorylation | organelle organization | regulation of transport | negative regulation of cell proliferation | cellular metal ion homeostasis | positive regulation of metabolic process | positive regulation of growth hormone secretion | divalent inorganic cation homeostasis | positive regulation of signaling | signal transduction | regulation of signaling | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

apical plasma membrane | neuron projection | somatodendritic compartment | cell body | cell | neuronal cell body | cytoplasm | apical part of cell | cell projection | plasma membrane | extracellular region | extracellular space | cell periphery | intracellular | membrane