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4-1BB
(gene)
Summary
General Info
Body Atlas
Most Correlated Tissues
Neutrophil of bone marrow
Microglial cell
Leukocyte (polymorphonuclear) of peripheral blood
Ciliary ganglion
Lymph nodes
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Disease Atlas
Most Correlated Diseases
Lymphoproliferative disorder
Measles
Infection due to Mycobacterium tuberculosis
Toxoplasmosis
Bacterial infection due to Bacillus
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Pharmaco Atlas
Most Correlated Compounds
Interleukin-18
TNFSF12 protein, human
Antigens, CD3
Dicarbethoxydihydrocollidine
Cytokines
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Knockdown Atlas
Most Correlated Gene Perturbations
ZFP90
ROBO1
POU2AF1
TNFRSF9
CD247
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Curated Studies
Most Correlated Studies
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Literature
Most Relevant Literature
Exosome derived from CD137-modified endothelial cells regulates the Th17 responses in atherosclerosi…
CD137 agonist-based combination immunotherapy enhances activated, effector memory T cells and prolon…
Combined congenic mapping and nuclease-based gene targeting for studying allele-specific effects of …
Therapeutic potential of anti-CD137 (4-1BB) monoclonal antibodies.
The Murine CD137/CD137 Ligand Signalosome: A Signal Platform Generating Signal Complexity.
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Clinical Trials
Most Relevant Clinical Trials
Study Of OX40 Agonist PF-04518600 Alone And In Combination With 4-1BB Agonist PF-05082566
Study of YH004 (4-1BB Agonist Antibody) in Advanced or Metastatic Malignancy
Study of Redirected Autologous T Cells Engineered to Contain Anti-CD19 Attached to TCR and 4-1BB Sig…
A Study Of 4-1BB Agonist PF-05082566 Plus PD-1 Inhibitor MK-3475 In Patients With Solid Tumors (B164…
Anti-CD19, Dual Co-stimulatory (4-1BB, CD3ζ) Chimeric Antigen Receptor T-cells in Patients With Rela…
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