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QuickView for AMD3100 (compound)


Genetic Markers

Most Correlated Genes

  1. Scd1
  2. SLC7A3
  3. HIST1H2AM
  4. TRIB3
  5. FAM129A
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Pathway Enrichment

Most Correlated Biogroups

  1. regulation of nitrogen compound metabolic process
  2. organic cyclic compound binding
  3. heterocyclic compound binding
  4. cytosol
  5. organic cyclic compound metabolic process
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Curated Studies

Most Correlated Studies

  1. T-cell acute lymphoblastic leukemia (T-ALL) cells CXCR4 inhibitor treated, or from CXCR4 KO mice
  2. Blood and bone marrow CD34+ hematopoietic stem cells from sickle cell disease patients
  3. MicroRNA profiling of mobilized-peripheral blood hematopoietic stem cells
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Literature

Most Relevant Literature

  1. AMD3100-Mediated CXCR4 Inhibition Impairs Development of Primary Lymphoma of the Central Nervous Sys…
  2. Use of plerixafor to mobilize haematopoietic progenitor cells in healthy donors.
  3. Plerixafor stem cell mobilization in Japanese children: A post-marketing study.
  4. Comparison of the Response to the CXCR4 Antagonist AMD3100 during the Development of Retinal Organoi…
  5. Mobilized and apheresis-collected endothelial progenitor cells with plerixafor.
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Clinical Trials

Most Relevant Clinical Trials

  1. AMD3100 Plus Mitoxantrone, Etoposide and Cytarabine in Acute Myeloid Leukemia
  2. Intravenous (IV) AMD3100 for Mobilization and Matched Related Transplant for Advanced Hematological …
  3. AMD3100 for Sensitizing in Allogeneic Blood or Marrow Transplant for Chemotherapy Resistant Pediatri…
  4. An Evaluation of Safety and Efficacy of Escalating Doses of AMD3100 to Mobilize CD34+ Cells in Healt…
  5. Study Evaluating AMD3100 for Transplantation of Sibling Donor Stem Cells in Patients With Hematologi…
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