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ANGPTL3
(gene)
Summary
General Info
Body Atlas
Most Correlated Tissues
Liver
Fetal liver
Kidney cortex
Myeloid cells of peripheral blood
Skeletal muscle psoas
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Disease Atlas
Most Correlated Diseases
Abetalipoproteinemia
Familial lipoprotein deficiency
Gastrointestinal hemorrhage
Encephalomyelitis
Acute hepatic failure
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Pharmaco Atlas
Most Correlated Compounds
N-nitrosopiperidine
presurface protein 1, hepatitis B surface antigen
4,4'-diaminodiphenylmethane
methyl carbamate
4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone
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Knockdown Atlas
Most Correlated Gene Perturbations
PECR
RPIA
ATF6
GBA
LEPR
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Curated Studies
Most Correlated Studies
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Literature
Most Relevant Literature
METTL3 regulates N6-methyladenosine modification of ANGPTL3 mRNA and potentiates malignant progressi…
The Fibrinogen-like Domain of ANGPTL3 Facilitates Lipolysis in 3T3-L1 Cells by Activating the Intrac…
Angiopoietin-like 3 inhibition of endothelial lipase is not modulated by angiopoietin-like 8.
ANGPTL3 is involved in kidney injury in high-fat diet-fed mice by suppressing ACTN4 expression.
Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in …
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Clinical Trials
Most Relevant Clinical Trials
Physiological Effects of ANGPTL3 Variants in Humans
Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS ANGPTL3-LRx in Healthy Volunte…
Phase 2 Study of AKCEA-ANGPTL3-LRX (ISIS 703802) in Patients With Familial Chylomicronemia Syndrome …
In Vivo Metabolism of apoB-containing Lipoproteins in ANGPTL3 Deficient Subjects
Serum ANGPTL3, ANGPTL8 and Glypican 4 Concentrations in Relation to the Development of Obesity in Ko…
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