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QuickView for AS1411 (compound)


Genetic Markers

Most Correlated Genes

  1. CYB5R3
  2. FKBP1A
  3. ARHGDIA
  4. TMEM230
  5. CLDN3
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Pathway Enrichment

Most Correlated Biogroups

  1. DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP
  2. KINSEY_TARGETS_OF_EWSR1_FLII_FUSION_UP
  3. SENESE_HDAC1_TARGETS_UP
  4. RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_UP
  5. PILON_KLF1_TARGETS_DN
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Curated Studies

Most Correlated Studies

  1. Breast cancer MCF7 cells treated with nucleolin (NCL) binding aptamers
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Literature

Most Relevant Literature

  1. The effect of AS1411 surface density on the tumor targeting properties of PEGylated silver nanotrian…
  2. Progress in cancer drug delivery based on AS1411 oriented nanomaterials.
  3. Insights on the molecular mechanisms of cytotoxicity induced by AS1411 linked to folate-functionaliz…
  4. AS1411-conjugated doxorubicin-loaded silver nanotriangles for targeted chemo-photothermal therapy of…
  5. Anti-Proliferative Effect of Doxorubicin-Loaded AS1411 Aptamer on Colorectal Cancer Cell.
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Clinical Trials

Most Relevant Clinical Trials

  1. Study of AS1411 in Advanced Solid Tumours
  2. A Phase II Study of AS1411 in Renal Cell Carcinoma
  3. A Study of AS1411 Combined With Cytarabine in the Treatment of Patients With Primary Refractory or R…
  4. Phase II Study of AS1411 Combined With Cytarabine to Treat Acute Myeloid Leukemia
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