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Abatacept
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
CD80
CD86
HIST1H3G
MYH2
HIST1H2AJ
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Pathway Enrichment
Most Correlated Biogroups
TTTNNANAGCYR_UNKNOWN
REACTOME_IMMUNE_SYSTEM
GAL_LEUKEMIC_STEM_CELL_DN
immune response
positive regulation of immune system process
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Curated Studies
Most Correlated Studies
CD4-positive T cells and antigen presenting cells from OVA TCR mice treated with abatacept
Whole blood of rheumatoid arthritis patients treated with abatacept
T-cells expression after treatment with leukocyte costimulatory blockade antibodies
Drug target sets for approved compounds
Germinal B cells from spleen of systemic lupus erythematosus mice treated with CTLA4Ig & anti-CD40L
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Literature
Most Relevant Literature
Predictive value of baseline concomitant glucocorticoid for abatacept-mediated long-term inhibition …
Efficacy and safety of abatacept to treat active birdshot uveitis: a prospective open label interven…
Rapid response to abatacept in treatment-resistant pansclerotic morphoea.
Abatacept in usual and in non-specific interstitial pneumonia associated with rheumatoid arthritis.
Efficacy and safety of abatacept for interstitial lung disease associated with antisynthetase syndro…
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Clinical Trials
Most Relevant Clinical Trials
Abatacept in Juvenile Dermatomyositis
Abatacept Conversion in Kidney Transplantation
Abatacept in ANCA Associated Vasculitis
Effects of Abatacept on Myocarditis in Rheumatoid Arthritis
Abatacept for the Treatment of Giant Cell Arteritis
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