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QuickView for Amprenavir (compound)


Genetic Markers

Most Correlated Genes

  1. PPP2CA
  2. CYP51A1
  3. ROCK2
  4. DLX5
  5. HMGCS1
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Pathway Enrichment

Most Correlated Biogroups

  1. cytosol
  2. DIAZ_CHRONIC_MEYLOGENOUS_LEUKEMIA_UP
  3. response to organic substance
  4. response to stress
  5. BLALOCK_ALZHEIMERS_DISEASE_UP
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Curated Studies

Most Correlated Studies

  1. Liver tissues from rats after treatment with different compounds
  2. Drug Matrix In Vivo Toxicogenomic Study - Rat Kidney [Codelink]
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Literature

Most Relevant Literature

  1. The HIV - 1 protease inhibitor Amprenavir targets Leishmania donovani topoisomerase I and induces ox…
  2. Insights into effect of the Asp25/Asp25' protonation states on binding of inhibitors Amprenavir and …
  3. In-vitro dynamic dissolution/bioconversion/permeation of fosamprenavir using a novel tool with an ar…
  4. Isolation of MDCK cells with low expression of mdr1 gene and their use in membrane permeability scre…
  5. Repositioning of amprenavir as a novel extracellular signal-regulated kinase-2 inhibitor and apoptos…
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Clinical Trials

Most Relevant Clinical Trials

  1. A Study of Amprenavir in HIV-Infected Patients
  2. Continued Antiretroviral Therapy With Abacavir, Amprenavir and Efavirenz
  3. A Study of Three Anti-HIV Drug Combinations in Patients Who Have Taken Amprenavir
  4. Salvage Therapy With Amprenavir, Lopinavir and Ritonavir in HIV-Infected Patients in Virological Fai…
  5. A Study of Amprenavir in Patients With Protease Inhibitor-Related Complications
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