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QuickView for B-Raf proteins


Curated Studies

Most Correlated Studies

  1. Antitumor efficacy of GDC-0879 involving BRAF mutational status
  2. Lung tumors from KRAS G12D expressing mice treated with N-acetylcysteine (NAC) or vitamin E
  3. Liver tumors expression profiles in mice
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Literature

Most Relevant Literature

  1. Preclinical efficacy of carfilzomib in BRAF-mutant colorectal cancer models.
  2. Efficacy of BRAF/MEK-inhibitor therapy for epithelioid glioblastoma with a novel BRAFV600 mutation.
  3. Computational analysis of natural product B-Raf inhibitors.
  4. Design, synthesis and characterisation of a novel type II B-RAF paradox breaker inhibitor.
  5. Evaluation of circulating tumor DNA as a prognostic and predictive biomarker in BRAF V600E mutated c…
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Clinical Trials

Most Relevant Clinical Trials

  1. Evaluation of Pathway Modulation by Raf, MEK, & Kinase Inhibitors
  2. Study of IK-595 in RAS- or RAF-altered Advanced Tumors
  3. Trametinib + HDM201 in CRC Patients With RAS/RAF Mutant and TP53 Wild-type Advanced/Metastatic Color…
  4. Selumetinib in Treating Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma
  5. Randomized Phase II Study of AZD6244 (Mitogen-activated Protein Kinase Inhibitor) MEK-Inhibitor With…
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