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BRCA2 protein
(compound)
Summary
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Genetic Markers
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Pathway Enrichment
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Curated Studies
Most Correlated Studies
Mammary gland epithelial HME1 cells cultured in EGF-free medium after recovery from BRCA2-depletion
Mammary gland hTert HME1 cells with BRCA2 siRNA knockdown grown in media with EGF
Melanoma biopsies of patients pre anti-PD-1 therapy with Pembrolizumab
Anaplastic thyroid cancer SW1736 cells overexpressing thyroid hormone receptor beta (TRB)
Ovarian cancer of Lynch syndrome patients compared to sporadic ovarian cancers
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Literature
Most Relevant Literature
The BRCA2 and CDKN1A-interacting protein (BCCIP) stabilizes stalled replication forks and prevents d…
Visualization of direct and diffusion-assisted RAD51 nucleation by full-length human BRCA2 protein.
Determinants governing BRC function evaluated by mutational analysis of Brh2 in Ustilago maydis.
Acquired cross-linker resistance associated with a novel spliced BRCA2 protein variant for molecular…
Intracellular location of BRCA2 protein expression and prostate cancer progression in the Swedish Wa…
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Clinical Trials
Most Relevant Clinical Trials
Study With Trabectedin in BRCA1 and BRCA2 Mutation Carrier and BRCAness Phenotype Ovarian Cancer
Olaparib, Durvalumab, and Tremelimumab in Treating Patients With Recurrent or Refractory Ovarian, Fa…
A Study to Assess the Safety and Pharmacokinetics of an Inhibitor of Poly ADP-Ribose Polymerase-1 (P…
Evaluation of Tomosynthesis for Characterization and the Management of Breast Lesions
Transformation Potential of E2 Exposed Breast Cancer Susceptibility Gene Mutation Heterozygous Epith…
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