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QuickView for Bcl-2 (gene)


Body Atlas

Most Correlated Tissues

  1. T Lymphocyte (regulatory) of peripheral blood
  2. T Lymphocyte (CD4+) of peripheral blood
  3. Basophil of peripheral blood
  4. Thyroid gland
  5. B lymphocyte (IgM memory) of spleen
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Disease Atlas

Most Correlated Diseases

  1. Other leukemia
  2. Graft versus host disease
  3. B-cell lymphoma
  4. Heart failure
  5. Endocarditis
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Pharmaco Atlas

Most Correlated Compounds

  1. bromohydrin pyrophosphate
  2. Interleukin-2
  3. 17-hydroxyandrostane-3-glucuronide
  4. acteoside
  5. IL10 protein, human
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. LOC633719
  2. CASP8AP2
  3. PITX2
  4. IGH
  5. PPP2R2D
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Bcl-2-negative IGH-BCL2 translocation-negative follicular lymphoma of the thyroid differs geneticall…
  2. Targeting Bcl-2 for cancer therapy.
  3. Expression of Apoptotic Markers Bcl-2 and Bax in the Vascular Wall.
  4. Decreased BIM expression in BCL2-negative follicular lymphoma: a potential mechanism for resistance …
  5. Phosphorylation of BCL2 at the Ser70 site mediates RANKL-induced osteoclast precursor autophagy and …
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Clinical Trials

Most Relevant Clinical Trials

  1. Use of Venetoclax as Single Agent in Patients With Relapsed/Refractory BCL-2 Positive Peripheral T C…
  2. Palbociclib, Letrozole & Venetoclax in ER and BCL-2 Positive Breast Cancer
  3. Italian Observational Study of Patients With Acute Myeloid Leukemia Treated With Small Molecule Inhi…
  4. Study of Bcl-2 Inhibitor BGB-11417 in Participants With Mature B-Cell Malignancies
  5. ACVBP Followed by ASCT in Patients With BCL-2 Positive Diffuse Large B-Cell Lymphoma
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