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QuickView for Bcl-2 (gene)


Body Atlas

Most Correlated Tissues

  1. T Lymphocyte (regulatory) of peripheral blood
  2. T Lymphocyte (CD4+) of peripheral blood
  3. Basophil of peripheral blood
  4. Thyroid gland
  5. B lymphocyte (IgM memory) of spleen
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Disease Atlas

Most Correlated Diseases

  1. Other leukemia
  2. Graft versus host disease
  3. B-cell lymphoma
  4. Vesicular stomatitis Indiana virus disease
  5. Heart failure
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Pharmaco Atlas

Most Correlated Compounds

  1. bromohydrin pyrophosphate
  2. 17-hydroxyandrostane-3-glucuronide
  3. Interleukin-2
  4. acteoside
  5. IL10 protein, human
Explore Pharmaco Atlas Results

Knockdown Atlas

Most Correlated Gene Perturbations

  1. LOC633719
  2. CASP8AP2
  3. PITX2
  4. IGH
  5. PPP2R2D
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. bcl-2 and p53 as novel biomarkers for predicting malignant transformation in chronic osteomyelitis.
  2. Targeting RNA Splicing Overcomes Leukemia Resistance to BCL2 Inhibition.
  3. Yeast Bax Inhibitor (Bxi1p/Ybh3p) Is Not Required for the Action of Bcl-2 Family Proteins on Cell Vi…
  4. Anti-apoptotic Bcl-2 protein in apo and holo conformation anchored to the membrane: comparative mole…
  5. DNAi-peptide nanohybrid smart particles target BCL-2 oncogene and induce apoptosis in breast cancer …
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Clinical Trials

Most Relevant Clinical Trials

  1. Use of Venetoclax as Single Agent in Patients With Relapsed/Refractory BCL-2 Positive Peripheral T C…
  2. Palbociclib, Letrozole & Venetoclax in ER and BCL-2 Positive Breast Cancer
  3. Italian Observational Study of Patients With Acute Myeloid Leukemia Treated With Small Molecule Inhi…
  4. Study of Bcl-2 Inhibitor BGB-11417 in Participants With Mature B-Cell Malignancies
  5. Phase 1 Study of BGB-21447, a Bcl-2 Inhibitor, in Mature B-Cell Malignancies
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