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CDDO-IM
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
FABP4
NNMT
CA3
CXCL1
CES3
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Pathway Enrichment
Most Correlated Biogroups
REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE
REACTOME_TRANSLATION
REACTOME_METABOLISM_OF_PROTEINS
mitochondrion
REACTOME_PEPTIDE_CHAIN_ELONGATION
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Curated Studies
Most Correlated Studies
Livers of Nrf2 null mice administered CDDO-Imidazolide
Genetic and pharmacologic activation of Nrf2 signaling in mouse liver
Liposarcoma cell line LiSa-2 responses to treatment with the synthetic triterpenoid CDDO
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Literature
Most Relevant Literature
Uncovering the anti-angiogenic effect of semisynthetic triterpenoid CDDO-Im on HUVECs by an integrat…
Triterpenoid CDDO-IM protects against lipopolysaccharide-induced inflammatory response and cytotoxic…
CDDO-Im ameliorates osteoarthritis and inhibits chondrocyte apoptosis in mice via enhancing Nrf2-dep…
CDDO-Im is a stimulator of megakaryocytic differentiation.
CDDO-Im exerts antidepressant-like effects via the Nrf2/ARE pathway in a rat model of post-stroke de…
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Clinical Trials
Most Relevant Clinical Trials
CDDO to Treat Solid Tumors and Lymphomas
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