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QuickView for CES1 (gene)


Body Atlas

Most Correlated Tissues

  1. Liver
  2. Adipose tissue subcutaneous
  3. Bronchus
  4. Trachea
  5. Lung
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Disease Atlas

Most Correlated Diseases

  1. Deficiency of carboxylesterase
  2. Hyperoxia
  3. Diarrhea
  4. Anthrax
  5. Encephalomyelitis
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Pharmaco Atlas

Most Correlated Compounds

  1. AS 605240
  2. AT 7519
  3. BGJ398
  4. Canertinib
  5. DCC-2036
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. PARL
  2. PLEKHJ1
  3. GTPBP8
  4. HEY1
  5. DMTF1
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. The COVID-19 Oral Drug Molnupiravir Is a CES2 Substrate: Potential Drug-Drug Interactions and Impact…
  2. Major implications of single nucleotide polymorphisms in human carboxylesterase 1 on substrate bioav…
  3. Evaluation of the inhibitory effects of antigout drugs on human carboxylesterases in vitro.
  4. Characterization of Oncolytic Vaccinia Virus Harboring the Human IFNB1 and CES2 Transgenes.
  5. Variability in plasma rifampicin concentrations and role of SLCO1B1, ABCB1, AADAC2 and CES2 genotype…
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Clinical Trials

Most Relevant Clinical Trials

  1. CES1 Crossover Trial of Clopidogrel and Ticagrelor
  2. Impact of CES1 Genotype on Metabolism of Methylphenidate
  3. Metabolism of Methylphenidate and Enalapril Based on CES1 Genotype
  4. Impact of CES1 Genotype on Remimazolam
  5. Characterisation of the Human Carboxylesterase 1 (CES1) Mutations in Thailand
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