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Cwc25
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Summary
General Info
Body Atlas
Most Correlated Tissues
Atrioventricular node
Leukocyte (polymorphonuclear) of peripheral blood
Superior cervical ganglion
Neutrophil of bone marrow
Ciliary ganglion
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Disease Atlas
Most Correlated Diseases
Traumatic injury
Mood disorder
Mental state, behavior and/or psychosocial function finding
General adaptation syndrome
Liver transplant disorder
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Pharmaco Atlas
Most Correlated Compounds
1-(5-(2-thenyloxy)-1H-indol-3-yl)propan-2-amine
nipecotic acid
leucodin
Hydrocortisone
Ceftazidime
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Knockdown Atlas
Most Correlated Gene Perturbations
SRF
SETBP1
YAF2
KIF5B
MAPK14
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Curated Studies
Most Correlated Studies
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Literature
Most Relevant Literature
A central role of Cwc25 in spliceosome dynamics during the catalytic phase of pre-mRNA splicing.
Cryo-EM structure of the spliceosome immediately after branching.
Biased Brownian ratcheting leads to pre-mRNA remodeling and capture prior to first-step splicing.
Link of NTR-mediated spliceosome disassembly with DEAH-box ATPases Prp2, Prp16, and Prp22.
The spliceosome catalyzes debranching in competition with reverse of the first chemical reaction.
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Clinical Trials
Most Relevant Clinical Trials
There were no clinical trials for Cwc25
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