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DNA mismatch repair
NextBio Summary
General Info
Curated Studies
Most Correlated Studies
Colorectal cancer cell lines with and without DNA replication errors
Colorectal cancers with microsatellite instability caused by defective mismatch repair
B cell lymphoma CH12.F3 cells undergoing IgA class switching Mbd4 knockout or wildtype
Lung NCI-H441 cells with MSH2 + MSH6 siRNA knockdown then infected with influenza A virus
Glioma cancer stem cells and matched non-cancer stem cells from glioblastoma patients
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Literature
Most Relevant Literature
Diagnostic challenges in a CMMRD patient with a novel mutation in the PMS2 gene: a case report.
Germline Biallelic Mismatch Repair Deficiency in Childhood Glioblastoma and Implications for Clinica…
Diagnostic criteria for constitutional mismatch repair deficiency (CMMRD): recommendations from the …
PMS2 expression decrease causes severe problems in mismatch repair.
Universal tumor screening in a population with MSH6- and PMS2-associated Lynch syndrome.
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Clinical Trials
Most Relevant Clinical Trials
Naproxen in Preventing DNA Mismatch Repair Deficient Colorectal Cancer in Patients With Lynch Syndro…
Combination Chemotherapy, Bevacizumab, and/or Atezolizumab in Treating Patients With Deficient DNA M…
Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Canc…
IBI310 in Combination With Sintilimab in Patients With DNA Mismatch Repair Deficient(dMMR)/Microsate…
The mCRC Patients With pMMR/MSS or dMMR/MSI-H Status Received Palliative Chemotherapy Efficacy and S…
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