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QuickView for DNMT3A (gene)


Body Atlas

Most Correlated Tissues

  1. Placenta
  2. Thymus gland
  3. Granulocyte-macrophage progenitor cell of bone marrow
  4. Skeletal muscle
  5. Endometrium
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Disease Atlas

Most Correlated Diseases

  1. Centromeric instability of chromosomes 1,9 and 16 and immunodeficiency
  2. Muscle atrophy
  3. Stachybotryotoxicosis
  4. Disorder of intraocular pressure
  5. Neurological finding
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Pharmaco Atlas

Most Correlated Compounds

  1. methylazoxymethanol
  2. Midodrine
  3. Oxyphenisatin Acetate
  4. diacetylrhein
  5. Angiotensins
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Knockdown Atlas

Most Correlated Gene Perturbations

  1. Pparg
  2. DIABLO
  3. MGMT
  4. HK2
  5. Alkbh1
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Curated Studies

Most Correlated Studies

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Literature

Most Relevant Literature

  1. Hematopoietic-specific heterozygous loss of Dnmt3a exacerbates colitis-associated colon cancer.
  2. WT1 and DNMT3A Mutations in Prognostic Significance of Acute Myeloid Leukemia: A Meta-Analysis.
  3. Transcriptional and functional consequences of Oncostatin M signaling on young Dnmt3a-mutant hematop…
  4. Research progress on DNMT3A gene expression in Acute myeloid leukemia].
  5. Double mutant DNMT3A AML: a unique subtype experiencing increased DNA damage and poor prognosis.
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Clinical Trials

Most Relevant Clinical Trials

  1. Prophylactic Donor Lymphocyte Infusion After Allo-PBSCT for Patients With Very High-risk Hematologic…
  2. Effect of DNMT SNPs on DNA Methylation in Primary ITP
  3. A Study to Investigate the Efficacy, Safety, and Tolerability of DFV890 and MAS825 for Inflammatory …
  4. Clonal Hematopoiesis of Indeterminate Potential in Venous Thromboembolism
  5. Prevalence and Clinical Effect of IDH1/2 Mutations in Patients With Acute Myeloid Leukemia
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