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Dinaciclib
(compound)
Summary
General Info
Genetic Markers
Most Correlated Genes
F13A1
MUC4
TCIM
XIST
SERPINB3
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Pathway Enrichment
Most Correlated Biogroups
regulation of nitrogen compound metabolic process
cytosol
nucleoplasm
vesicle
regulation of RNA biosynthetic process
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Curated Studies
Most Correlated Studies
Breast adenocarcinoma MDA-MB-231 cells treated with CDK12 inhibitor dinaciclib
Thyroid cancer TT and MZ-CRC-1 cells treated with dinaciclib
L1000 CMAP - Motor neuron MNEU.E cells treated with small molecule perturbagens
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (3 of 4)
L1000 CMAP - Breast cancer MCF7 cells treated with small molecule perturbagens (2 of 4)
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Literature
Most Relevant Literature
Reporting dinaciclib and theodrenaline as a multitargeted inhibitor against SARS-CoV-2: an in-silico…
Structural basis of CDK3 activation by cyclin E1 and inhibition by dinaciclib.
Pembrolizumab plus dinaciclib in patients with hematologic malignancies: the phase 1b KEYNOTE-155 st…
Pre-therapeutic efficacy of the CDK inhibitor dinaciclib in medulloblastoma cells.
Sensitization of cervical cancer cells to radiation by the cyclin-dependent kinase inhibitor dinacic…
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Clinical Trials
Most Relevant Clinical Trials
Veliparib and Dinaciclib in Treating Patients With Advanced Solid Tumors
Dinaciclib, Bortezomib, and Dexamethasone in Treating Patients With Relapsed Multiple Myeloma
Dinaciclib and Akt Inhibitor MK2206 in Treating Patients With Pancreatic Cancer That Cannot Be Remov…
Dinaciclib and Epirubicin Hydrochloride in Treating Patients With Metastatic Triple-Negative Breast …
Dinaciclib in Treating Patients With Stage IV Melanoma
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