QuickView for Fep1 (gene)

1. S. pombe dcr1, pmc6 or med20 deletion mutants or wildtype
2. S. pombe with mutations in MYST and GNAT family acyl transferases
3. S. pombe of wildtype or pap1-deleted strains treated with DETANONOate
4. Yeast cultured in nutrient-limiting conditions with snf1-deletions and inositol/choline treatment.
5. S. pombe cells with isp7+ knockout

1. Iron homeostasis proteins Grx4 and Fra2 control activity of the Schizosaccharomyces pombe iron repre…
2. The iron uptake repressor Fep1 in the fission yeast binds Fe-S cluster through conserved cysteines.
3. The flavohemoglobin Yhb1 is a new interacting partner of the heme transporter Str3.
4. Fra2 is a co-regulator of Fep1 inhibition in response to iron starvation.
5. FE UPTAKE-INDUCING PEPTIDE1 maintains Fe translocation by controlling Fe deficiency response genes i…

There were no clinical trials for Fep1