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Frontotemporal Dementia
(phenotype)
Summary
General Info
Genetic Markers
Most Correlated Genes
Most Correlated SNPs
VCP
GRN
RPE65
TBK1
MAPT
No SNPs found
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Pathway Enrichment
Most Correlated Biogroups
response to stress
GGGCGGR_SP1_Q6
DODD_NASOPHARYNGEAL_CARCINOMA_UP
response to organic substance
regulation of nucleic acid-templated transcription
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Curated Studies
Most Correlated Studies
Neurons differentiated from iPSCs of frontotemporal dementia patients with or without GRN mutations
Spinal cords from mice injected with antisense oligonucleotide targeting mouse C9orf72
Median temporal lobe tissues from normal subjects and patients with neurodegenerative diseases
OMIM - Hereditary inclusion body myopathy
Cerebella of patients with amyotrophic lateral sclerosis and frontotemporal dementia
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Literature
Most Relevant Literature
C9ORF72 repeat expansion in Australian and Spanish frontotemporal dementia patients.
Frontotemporal dementia as a frontostriatal disorder: neostriatal morphology as a biomarker and stru…
How do C9ORF72 repeat expansions cause amyotrophic lateral sclerosis and frontotemporal dementia: c…
Frontotemporal dementia caused by CHMP2B mutations.
Screening of the PFN1 gene in sporadic amyotrophic lateral sclerosis and in frontotemporal dementia.
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Clinical Trials
Most Relevant Clinical Trials
Low-Dose Lithium for the Treatment of Behavioral Symptoms in Frontotemporal Dementia
Open Label Pilot Study of the Effects of Memantine on FDG-PET in Frontotemporal Dementia
Dopaminergic Therapy for Frontotemporal Dementia Patients
Epidemiological Study in FRONtoTemporal Dementia
Living With Frontotemporal Dementia
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